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2vrf

From Proteopedia

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(New page: 200px <!-- The line below this paragraph, containing "STRUCTURE_2vrf", creates the "Structure Box" on the page. You may change the PDB parameter (which sets the PD...)
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[[Image:2vrf.jpg|left|200px]]
 
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==CRYSTAL STRUCTURE OF THE HUMAN BETA-2-SYNTROPHIN PDZ DOMAIN==
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The line below this paragraph, containing "STRUCTURE_2vrf", creates the "Structure Box" on the page.
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<StructureSection load='2vrf' size='340' side='right'caption='[[2vrf]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2vrf]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VRF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2VRF FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
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{{STRUCTURE_2vrf| PDB=2vrf | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2vrf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vrf OCA], [https://pdbe.org/2vrf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2vrf RCSB], [https://www.ebi.ac.uk/pdbsum/2vrf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2vrf ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/SNTB2_HUMAN SNTB2_HUMAN] Adapter protein that binds to and probably organizes the subcellular localization of a variety of membrane proteins. May link various receptors to the actin cytoskeleton and the dystrophin glycoprotein complex. May play a role in the regulation of secretory granules via its interaction with PTPRN.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vr/2vrf_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2vrf ConSurf].
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<div style="clear:both"></div>
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'''CRYSTAL STRUCTURE OF THE HUMAN BETA-2-SYNTROPHIN PDZ DOMAIN'''
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==See Also==
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*[[Syntrophin|Syntrophin]]
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__TOC__
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==About this Structure==
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</StructureSection>
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2VRF is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VRF OCA].
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Arrowsmith, C H.]]
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[[Category: Arrowsmith CH]]
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[[Category: Bountra, C.]]
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[[Category: Bountra C]]
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[[Category: Cooper, C.]]
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[[Category: Cooper C]]
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[[Category: Doyle, D.]]
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[[Category: Doyle D]]
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[[Category: Edwards, A.]]
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[[Category: Edwards A]]
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[[Category: Elkins, J M.]]
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[[Category: Elkins JM]]
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[[Category: Murray, J.]]
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[[Category: Murray J]]
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[[Category: Oppermann, U.]]
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[[Category: Oppermann U]]
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[[Category: Pike, A C.W.]]
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[[Category: Pike ACW]]
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[[Category: Pilka, E S.]]
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[[Category: Pilka ES]]
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[[Category: Roos, A K.]]
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[[Category: Roos AK]]
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[[Category: Sun, Z.]]
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[[Category: Sun Z]]
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[[Category: Vondelft, F.]]
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[[Category: Von Delft F]]
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[[Category: Actin cytoskeleton]]
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[[Category: Actin-binding]]
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[[Category: Adapter protein]]
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[[Category: Alternative splicing]]
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[[Category: Calcium]]
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[[Category: Calmodulin-binding]]
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[[Category: Cytoplasm]]
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[[Category: Cytoplasmic vesicle]]
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[[Category: Cytoskeleton]]
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[[Category: Membrane]]
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[[Category: Microtubule]]
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[[Category: Phosphoprotein]]
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[[Category: Polymorphism]]
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[[Category: Protein-binding]]
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[[Category: Snt3]]
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[[Category: Sntb2]]
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[[Category: Sntl]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Apr 24 09:43:30 2008''
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Current revision

CRYSTAL STRUCTURE OF THE HUMAN BETA-2-SYNTROPHIN PDZ DOMAIN

PDB ID 2vrf

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