1zxj

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<StructureSection load='1zxj' size='340' side='right'caption='[[1zxj]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
<StructureSection load='1zxj' size='340' side='right'caption='[[1zxj]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1zxj]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/"filterable_agent_of_primary_atypical_pneumonia"_eaton_et_al._1944 "filterable agent of primary atypical pneumonia" eaton et al. 1944]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZXJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ZXJ FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1zxj]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycoplasma_pneumoniae Mycoplasma pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZXJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ZXJ FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1zxj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zxj OCA], [http://pdbe.org/1zxj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1zxj RCSB], [http://www.ebi.ac.uk/pdbsum/1zxj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1zxj ProSAT], [http://www.topsan.org/Proteins/BSGC/1zxj TOPSAN]</span></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1zxj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zxj OCA], [https://pdbe.org/1zxj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1zxj RCSB], [https://www.ebi.ac.uk/pdbsum/1zxj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1zxj ProSAT], [https://www.topsan.org/Proteins/BSGC/1zxj TOPSAN]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Y555_MYCPN Y555_MYCPN]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1zxj ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1zxj ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
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<div style="background-color:#fffaf0;">
 
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== Publication Abstract from PubMed ==
 
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The crystal structure of the hypothetical protein MPN555 from Mycoplasma pneumoniae (gi|1673958) has been determined to a resolution of 2.8 Angstrom using anomalous diffraction data at the Se-peak wavelength. Structure determination revealed a mostly alpha-helical protein with a three-lobed shape. The three lobes or fingers delineate a central binding groove and additional grooves between lobes 1 and 3 and between lobes 2 and 3. For one of the molecules in the asymmetric unit, the central binding pocket was filled with a peptide from the uncleaved N-terminal affinity tag. The MPN555 structure has structural homology to two bacterial chaperone proteins: SurA and trigger factor from Escherichia coli. The structural data and the homology to other chaperone proteins suggests an involvement in protein folding as a molecular chaperone for MPN555.
 
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Structure of the hypothetical Mycoplasma protein MPN555 suggests a chaperone function.,Schulze-Gahmen U, Aono S, Chen S, Yokota H, Kim R, Kim SH Acta Crystallogr D Biol Crystallogr. 2005 Oct;61(Pt 10):1343-7. Epub 2005, Sep 28. PMID:16204885<ref>PMID:16204885</ref>
 
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
 
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</div>
 
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<div class="pdbe-citations 1zxj" style="background-color:#fffaf0;"></div>
 
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== References ==
 
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<references/>
 
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Filterable agent of primary atypical pneumonia eaton et al. 1944]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Aono, S]]
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[[Category: Mycoplasma pneumoniae]]
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[[Category: Structural genomic]]
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[[Category: Aono S]]
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[[Category: Kim, R]]
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[[Category: Kim R]]
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[[Category: Kim, S H]]
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[[Category: Kim S-H]]
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[[Category: Schulze-Gahmen, U]]
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[[Category: Schulze-Gahmen U]]
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[[Category: Shengfeng, C]]
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[[Category: Shengfeng C]]
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[[Category: Yokota, H]]
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[[Category: Yokota H]]
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[[Category: Bsgc]]
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[[Category: Mostly alpha helical protein]]
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[[Category: PSI, Protein structure initiative]]
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[[Category: Tri-lobal structure]]
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[[Category: Unknown function]]
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Current revision

Crystal structure of the hypthetical Mycoplasma protein, MPN555

PDB ID 1zxj

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