6pih
From Proteopedia
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==Hexameric ArnA cryo-EM structure==  | ==Hexameric ArnA cryo-EM structure==  | ||
| - | <  | + | <SX load='6pih' size='340' side='right' viewer='molstar' caption='[[6pih]], [[Resolution|resolution]] 6.60Å' scene=''>  | 
== Structural highlights ==  | == Structural highlights ==  | ||
| - | <table><tr><td colspan='2'>[[6pih]] is a 12 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6PIH OCA]. For a <b>guided tour on the structure components</b> use [  | + | <table><tr><td colspan='2'>[[6pih]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_DH5alpha Escherichia coli DH5alpha]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6PIH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6PIH FirstGlance]. <br>  | 
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[  | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 6.6Å</td></tr>  | 
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6pih FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6pih OCA], [https://pdbe.org/6pih PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6pih RCSB], [https://www.ebi.ac.uk/pdbsum/6pih PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6pih ProSAT]</span></td></tr>  | ||
</table>  | </table>  | ||
== Function ==  | == Function ==  | ||
| - | [  | + | [https://www.uniprot.org/uniprot/ARNA_ECOLI ARNA_ECOLI] Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido-arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.<ref>PMID:11706007</ref> <ref>PMID:15695810</ref>   | 
| + | == References ==  | ||
| + | <references/>  | ||
__TOC__  | __TOC__  | ||
| - | </  | + | </SX>  | 
[[Category: Large Structures]]  | [[Category: Large Structures]]  | ||
| - | [[Category: Gehring  | + | [[Category: Gehring K]]  | 
| - | [[Category: Yang  | + | [[Category: Yang M]]  | 
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Current revision
Hexameric ArnA cryo-EM structure
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