6klt
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Troponin of cardiac thin filament in low-calcium state== | |
| + | <SX load='6klt' size='340' side='right' viewer='molstar' caption='[[6klt]], [[Resolution|resolution]] 12.00Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[6klt]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6KLT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6KLT FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 12Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6klt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6klt OCA], [https://pdbe.org/6klt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6klt RCSB], [https://www.ebi.ac.uk/pdbsum/6klt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6klt ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/TNNC1_MOUSE TNNC1_MOUSE] Troponin is the central regulatory protein of striated muscle contraction. Tn consists of three components: Tn-I which is the inhibitor of actomyosin ATPase, Tn-T which contains the binding site for tropomyosin and Tn-C. The binding of calcium to Tn-C abolishes the inhibitory action of Tn on actin filaments. | ||
| - | + | ==See Also== | |
| - | + | *[[Troponin 3D structures|Troponin 3D structures]] | |
| - | + | __TOC__ | |
| - | [[Category: | + | </SX> |
| + | [[Category: Large Structures]] | ||
| + | [[Category: Mus musculus]] | ||
| + | [[Category: Oda T]] | ||
| + | [[Category: Wakabayashi T]] | ||
| + | [[Category: Yanagisawa H]] | ||
Current revision
Troponin of cardiac thin filament in low-calcium state
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