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6pz9
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 6pz9 is ON HOLD Authors: Shyng, S.L., Yoshioka, C., Martin, G.M., Sung, M.W. Description: SUR1-RPG-ATP state Category: Unreleased Structures [[...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Cryo-EM structure of the pancreatic beta-cell SUR1 bound to ATP and repaglinide== | |
| + | <SX load='6pz9' size='340' side='right' viewer='molstar' caption='[[6pz9]], [[Resolution|resolution]] 3.65Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[6pz9]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Cricetus_cricetus Cricetus cricetus] and [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6PZ9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6PZ9 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.65Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=BJX:Repaglinide'>BJX</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6pz9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6pz9 OCA], [https://pdbe.org/6pz9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6pz9 RCSB], [https://www.ebi.ac.uk/pdbsum/6pz9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6pz9 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/ABCC8_CRICR ABCC8_CRICR] Subunit of the beta-cell ATP-sensitive potassium channel (KATP). Regulator of ATP-sensitive potassium channels and insulin release.[UniProtKB:Q09428] | ||
| - | + | ==See Also== | |
| - | + | *[[Potassium channel 3D structures|Potassium channel 3D structures]] | |
| - | + | __TOC__ | |
| - | [[Category: | + | </SX> |
| - | [[Category: | + | [[Category: Cricetus cricetus]] |
| - | [[Category: Shyng | + | [[Category: Large Structures]] |
| - | [[Category: Sung | + | [[Category: Rattus norvegicus]] |
| - | [[Category: | + | [[Category: Martin GM]] |
| + | [[Category: Shyng SL]] | ||
| + | [[Category: Sung MW]] | ||
| + | [[Category: Yoshioka C]] | ||
Current revision
Cryo-EM structure of the pancreatic beta-cell SUR1 bound to ATP and repaglinide
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