1w45

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<StructureSection load='1w45' size='340' side='right'caption='[[1w45]], [[Resolution|resolution]] 2.51&Aring;' scene=''>
<StructureSection load='1w45' size='340' side='right'caption='[[1w45]], [[Resolution|resolution]] 2.51&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1w45]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1W45 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1W45 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1w45]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1W45 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1W45 FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1w3w|1w3w]]</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.51&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1w45 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1w45 OCA], [http://pdbe.org/1w45 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1w45 RCSB], [http://www.ebi.ac.uk/pdbsum/1w45 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1w45 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1w45 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1w45 OCA], [https://pdbe.org/1w45 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1w45 RCSB], [https://www.ebi.ac.uk/pdbsum/1w45 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1w45 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/ANXA8_HUMAN ANXA8_HUMAN]] This protein is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade.
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[https://www.uniprot.org/uniprot/ANXA8_HUMAN ANXA8_HUMAN] This protein is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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<jmolCheckbox>
<jmolCheckbox>
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/w4/1w45_consurf.spt"</scriptWhenChecked>
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/w4/1w45_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Blondeau, K]]
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[[Category: Blondeau K]]
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[[Category: Dreyfuss, L]]
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[[Category: Dreyfuss L]]
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[[Category: Hofbauerova, K]]
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[[Category: Hofbauerova K]]
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[[Category: Lewit-Bentley, A]]
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[[Category: Lewit-Bentley A]]
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[[Category: Raguenes-Nicol, C]]
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[[Category: Raguenes-Nicol C]]
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[[Category: Renouard, M]]
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[[Category: Renouard M]]
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[[Category: Rety, S]]
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[[Category: Rety S]]
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[[Category: Russo-Marie, F]]
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[[Category: Russo-Marie F]]
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[[Category: Santos, J Sopkova-de Oliveira]]
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[[Category: Sopkova-de Oliveira Santos J]]
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[[Category: Annexin family]]
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[[Category: Calcium and phospholipid binding protein]]
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[[Category: Coagulation]]
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[[Category: Cxalcium and membrane- binding protein]]
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[[Category: Intact n-terminus]]
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Current revision

The 2.5 Angstroem structure of the K16A mutant of annexin A8, which has an intact N-terminus.

PDB ID 1w45

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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