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6rxt

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==Cryo-EM structure of the 90S pre-ribosome (Kre33-Noc4) from Chaetomium thermophilum, state A==
==Cryo-EM structure of the 90S pre-ribosome (Kre33-Noc4) from Chaetomium thermophilum, state A==
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<StructureSection load='6rxt' size='340' side='right'caption='[[6rxt]], [[Resolution|resolution]] 7.00&Aring;' scene=''>
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<SX load='6rxt' size='340' side='right' viewer='molstar' caption='[[6rxt]], [[Resolution|resolution]] 7.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6rxt]] is a 57 chain structure with sequence from [http://en.wikipedia.org/wiki/Chaetomium_thermophilum Chaetomium thermophilum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6RXT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6RXT FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6rxt]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Chaetomium_thermophilum Chaetomium thermophilum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6RXT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6RXT FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 7&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6rxt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6rxt OCA], [http://pdbe.org/6rxt PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6rxt RCSB], [http://www.ebi.ac.uk/pdbsum/6rxt PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6rxt ProSAT]</span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6rxt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6rxt OCA], [https://pdbe.org/6rxt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6rxt RCSB], [https://www.ebi.ac.uk/pdbsum/6rxt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6rxt ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/G0S3V7_CHATD G0S3V7_CHATD]] Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly.[PIRNR:PIRNR006515] [[http://www.uniprot.org/uniprot/PNO1_CHATD PNO1_CHATD]] Required for small ribosomal subunit (SSU) synthesis. Has a role in the processing of early nucleolar and late cytoplasmic pre-RNA species.[UniProtKB:Q99216] [[http://www.uniprot.org/uniprot/UTP11_CHATD UTP11_CHATD]] Involved in nucleolar processing of pre-18S ribosomal RNA.[UniProtKB:P34247]
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[https://www.uniprot.org/uniprot/G0SF93_CHATD G0SF93_CHATD]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 6rxt" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 6rxt" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Ribosome 3D structures|Ribosome 3D structures]]
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*[[Ribosome biogenesis protein 3D structures|Ribosome biogenesis protein 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
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</StructureSection>
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</SX>
[[Category: Chaetomium thermophilum]]
[[Category: Chaetomium thermophilum]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Beckmann, R]]
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[[Category: Beckmann R]]
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[[Category: Berninghausen, O]]
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[[Category: Berninghausen O]]
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[[Category: Cheng, J]]
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[[Category: Cheng J]]
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[[Category: Griesel, S]]
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[[Category: Griesel S]]
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[[Category: Hurt, E]]
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[[Category: Hurt E]]
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[[Category: Kellner, N]]
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[[Category: Kellner N]]
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[[Category: Ribosome]]
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[[Category: Ribosome biogenesis]]
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[[Category: Rrna]]
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Current revision

Cryo-EM structure of the 90S pre-ribosome (Kre33-Noc4) from Chaetomium thermophilum, state A

6rxt, resolution 7.00Å

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