Purine repressor

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**[[1dbq]] - EcPurR CBD + Mg - NMR<br />
**[[1dbq]] - EcPurR CBD + Mg - NMR<br />
**[[1jhz]] - EcPurR CBD (mutant) + Mg <br />
**[[1jhz]] - EcPurR CBD (mutant) + Mg <br />
-
**[[1o57]] - PurR - ''Bacillus subtilis''<br />
+
**[[1o57]] - BsPurR - ''Bacillus subtilis''<br />
*Purine repressor complex with DNA and nucleotide
*Purine repressor complex with DNA and nucleotide
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**[[2puc]], [[2puf]] - EcPurR (mutant) + DNA + guanine <br />
**[[2puc]], [[2puf]] - EcPurR (mutant) + DNA + guanine <br />
**[[1zay]] - EcPurR + DNA + hypoxanthine + di-imino-purine<br />
**[[1zay]] - EcPurR + DNA + hypoxanthine + di-imino-purine<br />
 +
**[[7rmw]] – BsPurR + PPGPP<br />
}}
}}
== References ==
== References ==
<references/>
<references/>
[[Category:Topic Page]]
[[Category:Topic Page]]

Current revision

Structure of E. coli purine processor complex with DNA and guanine (PDB entry 1wet)

Drag the structure with the mouse to rotate

3D structures of purine repressor

Updated on 08-February-2022

References

  1. Wilson HR, Turnbough CL Jr. Role of the purine repressor in the regulation of pyrimidine gene expression in Escherichia coli K-12. J Bacteriol. 1990 Jun;172(6):3208-13. PMID:1971621
  2. Schumacher MA, Glasfeld A, Zalkin H, Brennan RG. The X-ray structure of the PurR-guanine-purF operator complex reveals the contributions of complementary electrostatic surfaces and a water-mediated hydrogen bond to corepressor specificity and binding affinity. J Biol Chem. 1997 Sep 5;272(36):22648-53. PMID:9278422

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Michal Harel, Alexander Berchansky, Joel L. Sussman

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