5qtp
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 5qtp is ON HOLD Authors: Dubianok, Y., Krojer, T., Kovacs, H., Moriaud, F., Wright, N., Strain-Damerell, C., Burgess-Brown, N., Bountra, C., Arrowsm...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==PanDDA analysis group deposition -- Crystal Structure of NUDT5 in complex with AE-0227== | |
| - | + | <StructureSection load='5qtp' size='340' side='right'caption='[[5qtp]], [[Resolution|resolution]] 1.73Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5qtp]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5QTP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5QTP FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.73Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PWJ:8-chloro-6-(trifluoromethyl)imidazo[1,2-a]pyridine-7-carbonitrile'>PWJ</scene></td></tr> |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5qtp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5qtp OCA], [https://pdbe.org/5qtp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5qtp RCSB], [https://www.ebi.ac.uk/pdbsum/5qtp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5qtp ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| - | [[Category: | + | == Function == |
| - | [[Category: Burgess-Brown | + | [https://www.uniprot.org/uniprot/NUDT5_HUMAN NUDT5_HUMAN] Hydrolyzes with similar activities ADP-ribose ADP-mannose, ADP-glucose, 8-oxo-GDP and 8-oxo-dGDP. Can also hydrolyze other nucleotide sugars with low activity.<ref>PMID:17052728</ref> |
| - | [[Category: Dubianok | + | == References == |
| - | [[Category: Kovacs | + | <references/> |
| - | [[Category: | + | __TOC__ |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Arrowsmith CH]] |
| + | [[Category: Bountra C]] | ||
| + | [[Category: Burgess-Brown N]] | ||
| + | [[Category: Dubianok Y]] | ||
| + | [[Category: Edwards A]] | ||
| + | [[Category: Kovacs H]] | ||
| + | [[Category: Krojer T]] | ||
| + | [[Category: Moriaud F]] | ||
| + | [[Category: Strain-Damerell C]] | ||
| + | [[Category: Wright N]] | ||
| + | [[Category: Von Delft F]] | ||
Current revision
PanDDA analysis group deposition -- Crystal Structure of NUDT5 in complex with AE-0227
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