6rp3

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'''Unreleased structure'''
 
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The entry 6rp3 is ON HOLD until Paper Publication
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==Truncated Norcoclaurine synthase with reaction intermediate mimic==
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<StructureSection load='6rp3' size='340' side='right'caption='[[6rp3]], [[Resolution|resolution]] 1.81&Aring;' scene=''>
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Authors: Keep, N.H., Roddan, R., Sula, A.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[6rp3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thalictrum_flavum_subsp._glaucum Thalictrum flavum subsp. glaucum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6RP3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6RP3 FirstGlance]. <br>
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Description: Truncated Norcoclaurine synthase with reaction intermediate mimic
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.81&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=KCZ:4-[2-[[(2~{R})-2-phenylpropyl]amino]ethyl]benzene-1,2-diol'>KCZ</scene></td></tr>
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[[Category: Sula, A]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6rp3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6rp3 OCA], [https://pdbe.org/6rp3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6rp3 RCSB], [https://www.ebi.ac.uk/pdbsum/6rp3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6rp3 ProSAT]</span></td></tr>
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[[Category: Roddan, R]]
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</table>
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[[Category: Keep, N.H]]
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== Function ==
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[https://www.uniprot.org/uniprot/NCS_THLFG NCS_THLFG] Involved in the biosynthesis of the common precursor of all benzylisoquinoline alkaloids such as morphine, sanguinarine, codeine or berberine. Condenses dopamine and 4-hydroxyphenylacetaldehyde.<ref>PMID:17696451</ref> <ref>PMID:17900926</ref> <ref>PMID:18384289</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Thalictrum flavum subsp. glaucum]]
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[[Category: Keep NH]]
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[[Category: Roddan R]]
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[[Category: Sula A]]

Current revision

Truncated Norcoclaurine synthase with reaction intermediate mimic

PDB ID 6rp3

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