6tza
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==CryoEM reconstruction of ESCRT-III filament composed of IST1 NTD R16E K27E double mutant== | |
| + | <StructureSection load='6tza' size='340' side='right'caption='[[6tza]], [[Resolution|resolution]] 7.20Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[6tza]] is a 14 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6TZA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6TZA FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 7.2Å</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6tza FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6tza OCA], [https://pdbe.org/6tza PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6tza RCSB], [https://www.ebi.ac.uk/pdbsum/6tza PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6tza ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/IST1_HUMAN IST1_HUMAN] Proposed to be involved in specific functions of the ESCRT machinery. Is required for efficient abscission during cytokinesis, but not for HIV-1 budding. The involvement in the MVB pathway is not established. Involved in recruiting VPS4A and/or VPS4B to the midbody of dividing cells.<ref>PMID:19129479</ref> <ref>PMID:19129480</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[Increased sodium tolerance protein|Increased sodium tolerance protein]] | |
| - | + | == References == | |
| - | [[Category: | + | <references/> |
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Frost A]] | ||
| + | [[Category: Nguyen HC]] | ||
Current revision
CryoEM reconstruction of ESCRT-III filament composed of IST1 NTD R16E K27E double mutant
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