6e8o

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==Implication of MbtH-like proteins in crystallization of the independent NRPS A domains. Crystal structure of FscC: supporting rationale for revised mechanism of freestanding aryl acid adenylating enzymes.==
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==Crystal structure of aryl acid adenylating enzyme FscC from Fuscachelin NRPS in complex with AMP==
<StructureSection load='6e8o' size='340' side='right'caption='[[6e8o]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
<StructureSection load='6e8o' size='340' side='right'caption='[[6e8o]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6e8o]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6E8O OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6E8O FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6e8o]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermobifida_fusca_YX Thermobifida fusca YX]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6E8O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6E8O FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AMP:ADENOSINE+MONOPHOSPHATE'>AMP</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6e8o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6e8o OCA], [http://pdbe.org/6e8o PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6e8o RCSB], [http://www.ebi.ac.uk/pdbsum/6e8o PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6e8o ProSAT]</span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AMP:ADENOSINE+MONOPHOSPHATE'>AMP</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6e8o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6e8o OCA], [https://pdbe.org/6e8o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6e8o RCSB], [https://www.ebi.ac.uk/pdbsum/6e8o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6e8o ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q47NR5_THEFY Q47NR5_THEFY]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Bruner, S D]]
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[[Category: Thermobifida fusca YX]]
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[[Category: Zagulyaeva, A A]]
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[[Category: Bruner SD]]
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[[Category: Adenylation domain]]
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[[Category: Zagulyaeva AA]]
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[[Category: Ligase]]
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[[Category: Nrp]]
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[[Category: Siderophore biosynthesis]]
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[[Category: Thiolation state]]
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Crystal structure of aryl acid adenylating enzyme FscC from Fuscachelin NRPS in complex with AMP

PDB ID 6e8o

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