This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


6pwf

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (09:27, 20 March 2024) (edit) (undo)
 
(3 intermediate revisions not shown.)
Line 1: Line 1:
==Cryo-EM structure of the ATPase domain of chromatin remodeling factor ISWI bound to the nucleosome==
==Cryo-EM structure of the ATPase domain of chromatin remodeling factor ISWI bound to the nucleosome==
-
<StructureSection load='6pwf' size='340' side='right'caption='[[6pwf]], [[Resolution|resolution]] 4.07&Aring;' scene=''>
+
<SX load='6pwf' size='340' side='right' viewer='molstar' caption='[[6pwf]], [[Resolution|resolution]] 4.07&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[6pwf]] is a 11 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6PWF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6PWF FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[6pwf]] is a 11 chain structure with sequence from [https://en.wikipedia.org/wiki/Chaetomium_thermophilum Chaetomium thermophilum], [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6PWF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6PWF FirstGlance]. <br>
-
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6pwf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6pwf OCA], [http://pdbe.org/6pwf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6pwf RCSB], [http://www.ebi.ac.uk/pdbsum/6pwf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6pwf ProSAT]</span></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 4.07&#8491;</td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6pwf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6pwf OCA], [https://pdbe.org/6pwf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6pwf RCSB], [https://www.ebi.ac.uk/pdbsum/6pwf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6pwf ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/A0A0B4KFZ9_DROME A0A0B4KFZ9_DROME]] Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.[RuleBase:RU000528][SAAS:SAAS00581158]
+
[https://www.uniprot.org/uniprot/H3_DROME H3_DROME]
 +
 
 +
==See Also==
 +
*[[Histone 3D structures|Histone 3D structures]]
__TOC__
__TOC__
-
</StructureSection>
+
</SX>
 +
[[Category: Chaetomium thermophilum]]
 +
[[Category: Drosophila melanogaster]]
[[Category: Large Structures]]
[[Category: Large Structures]]
-
[[Category: Chittori, S]]
+
[[Category: Synthetic construct]]
-
[[Category: Subramaniam, S]]
+
[[Category: Chittori S]]
-
[[Category: Atp-dependent chromatin remodeler]]
+
[[Category: Subramaniam S]]
-
[[Category: Dna-binding protein]]
+
-
[[Category: Iswi]]
+
-
[[Category: Nucleosome]]
+
-
[[Category: Structural protein-dna complex]]
+

Current revision

Cryo-EM structure of the ATPase domain of chromatin remodeling factor ISWI bound to the nucleosome

6pwf, resolution 4.07Å

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools