This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


6qwb

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (12:09, 24 January 2024) (edit) (undo)
 
Line 3: Line 3:
<StructureSection load='6qwb' size='340' side='right'caption='[[6qwb]], [[Resolution|resolution]] 1.04&Aring;' scene=''>
<StructureSection load='6qwb' size='340' side='right'caption='[[6qwb]], [[Resolution|resolution]] 1.04&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[6qwb]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6QWB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6QWB FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[6qwb]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Klebsiella_pneumoniae Klebsiella pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6QWB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6QWB FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=JJT:(2~{S})-5-azanylidene-2-(piperidin-4-ylcarbamoyl)piperidine-1-carboxylic+acid'>JJT</scene>, <scene name='pdbligand=MK7:(2S,5R)-1-FORMYL-N-(PIPERIDIN-4-YL)-5-[(SULFOOXY)AMINO]PIPERIDINE-2-CARBOXAMIDE'>MK7</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.04&#8491;</td></tr>
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=JJT:(2~{S})-5-azanylidene-2-(piperidin-4-ylcarbamoyl)piperidine-1-carboxylic+acid'>JJT</scene>, <scene name='pdbligand=MK7:(2S,5R)-1-FORMYL-N-(PIPERIDIN-4-YL)-5-[(SULFOOXY)AMINO]PIPERIDINE-2-CARBOXAMIDE'>MK7</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6qwb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6qwb OCA], [http://pdbe.org/6qwb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6qwb RCSB], [http://www.ebi.ac.uk/pdbsum/6qwb PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6qwb ProSAT]</span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6qwb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6qwb OCA], [https://pdbe.org/6qwb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6qwb RCSB], [https://www.ebi.ac.uk/pdbsum/6qwb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6qwb ProSAT]</span></td></tr>
</table>
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/BLKPC_KLEPN BLKPC_KLEPN] Hydrolyzes carbapenems, penicillins, cephalosporins and monobactams with varying efficiency.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 17: Line 19:
</div>
</div>
<div class="pdbe-citations 6qwb" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 6qwb" style="background-color:#fffaf0;"></div>
 +
 +
==See Also==
 +
*[[Beta-lactamase 3D structures|Beta-lactamase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Beta-lactamase]]
+
[[Category: Klebsiella pneumoniae]]
[[Category: Large Structures]]
[[Category: Large Structures]]
-
[[Category: Hinchliffe, P]]
+
[[Category: Hinchliffe P]]
-
[[Category: Spencer, J]]
+
[[Category: Spencer J]]
-
[[Category: Tooke, C L]]
+
[[Category: Tooke CL]]
-
[[Category: Antibiotic resistance]]
+
-
[[Category: Antimicrobial protein]]
+
-
[[Category: Diazabicyclooctane]]
+
-
[[Category: Inhibitor]]
+
-
[[Category: Relebactam]]
+

Current revision

Crystal structure of KPC-4 complexed with relebactam (16 hour soak)

PDB ID 6qwb

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/6qwb"
Personal tools