2ix8

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==MODEL FOR EEF3 BOUND TO AN 80S RIBOSOME==
==MODEL FOR EEF3 BOUND TO AN 80S RIBOSOME==
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<StructureSection load='2ix8' size='340' side='right'caption='[[2ix8]], [[Resolution|resolution]] 6.00&Aring;' scene=''>
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<SX load='2ix8' size='340' side='right' viewer='molstar' caption='[[2ix8]], [[Resolution|resolution]] 9.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2ix8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IX8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2IX8 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2ix8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IX8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2IX8 FirstGlance]. <br>
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</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 9.9&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ix8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ix8 OCA], [http://pdbe.org/2ix8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2ix8 RCSB], [http://www.ebi.ac.uk/pdbsum/2ix8 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2ix8 ProSAT]</span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ix8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ix8 OCA], [https://pdbe.org/2ix8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ix8 RCSB], [https://www.ebi.ac.uk/pdbsum/2ix8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ix8 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/EF3A_YEAST EF3A_YEAST]] Required for the ATP-dependent release of deacylated tRNA from the ribosomal E-site during protein biosynthesis. Stimulates the eEF1A-dependent binding of aminoacyl-tRNA to the ribosomal A-site, which has reduced affinity for tRNA as long as the E-site is occupied.<ref>PMID:6456269</ref> <ref>PMID:7657623</ref>
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[https://www.uniprot.org/uniprot/EF3A_YEAST EF3A_YEAST] Required for the ATP-dependent release of deacylated tRNA from the ribosomal E-site during protein biosynthesis. Stimulates the eEF1A-dependent binding of aminoacyl-tRNA to the ribosomal A-site, which has reduced affinity for tRNA as long as the E-site is occupied.<ref>PMID:6456269</ref> <ref>PMID:7657623</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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<jmolCheckbox>
<jmolCheckbox>
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ix/2ix8_consurf.spt"</scriptWhenChecked>
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ix/2ix8_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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<references/>
<references/>
__TOC__
__TOC__
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</StructureSection>
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</SX>
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[[Category: Atcc 18824]]
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[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Anand, M]]
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[[Category: Saccharomyces cerevisiae]]
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[[Category: Andersen, C B.F]]
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[[Category: Anand M]]
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[[Category: Andersen, G R]]
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[[Category: Andersen CBF]]
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[[Category: Balar, B]]
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[[Category: Andersen GR]]
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[[Category: Becker, T]]
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[[Category: Balar B]]
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[[Category: Beckmann, R]]
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[[Category: Becker T]]
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[[Category: Blau, M]]
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[[Category: Beckmann R]]
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[[Category: Boesen, T]]
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[[Category: Blau M]]
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[[Category: Halic, M]]
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[[Category: Boesen T]]
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[[Category: Kinzy, T G]]
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[[Category: Halic M]]
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[[Category: Mielke, T]]
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[[Category: Kinzy TG]]
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[[Category: Pedersen, J S]]
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[[Category: Mielke T]]
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[[Category: Spahn, C M.T]]
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[[Category: Pedersen JS]]
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[[Category: Atp-binding]]
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[[Category: Spahn CMT]]
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[[Category: Elongation factor]]
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[[Category: Nucleotide-binding]]
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[[Category: Phosphorylation]]
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[[Category: Protein biosynthesis]]
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[[Category: Rna-binding]]
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[[Category: Rrna-binding]]
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Current revision

MODEL FOR EEF3 BOUND TO AN 80S RIBOSOME

2ix8, resolution 9.90Å

Proteopedia Page Contributors and Editors (what is this?)

OCA

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