6kp6
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | The | + | ==The structural study of mutation induced inactivation of Human muscarinic receptor M4== |
| + | <StructureSection load='6kp6' size='340' side='right'caption='[[6kp6]], [[Resolution|resolution]] 3.00Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[6kp6]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Pyrococcus_abyssi_GE5 Pyrococcus abyssi GE5]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6KP6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6KP6 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3Å</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6kp6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6kp6 OCA], [https://pdbe.org/6kp6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6kp6 RCSB], [https://www.ebi.ac.uk/pdbsum/6kp6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6kp6 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/ACM4_HUMAN ACM4_HUMAN] The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is inhibition of adenylate cyclase.[https://www.uniprot.org/uniprot/Q9V2J8_PYRAB Q9V2J8_PYRAB] | ||
| - | + | ==See Also== | |
| - | + | *[[Muscarinic acetylcholine receptor|Muscarinic acetylcholine receptor]] | |
| - | + | __TOC__ | |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Liu | + | [[Category: Pyrococcus abyssi GE5]] |
| - | [[Category: | + | [[Category: Hua T]] |
| - | [[Category: | + | [[Category: Liu ZJ]] |
| + | [[Category: Wang JJ]] | ||
| + | [[Category: Wu LJ]] | ||
| + | [[Category: Wu M]] | ||
Current revision
The structural study of mutation induced inactivation of Human muscarinic receptor M4
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Categories: Homo sapiens | Large Structures | Pyrococcus abyssi GE5 | Hua T | Liu ZJ | Wang JJ | Wu LJ | Wu M
