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6ptl

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'''Unreleased structure'''
 
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The entry 6ptl is ON HOLD until Paper Publication
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==Structure of the self-association domain of the chromatin looping factor LDB1==
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<StructureSection load='6ptl' size='340' side='right'caption='[[6ptl]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
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Authors: Macindoe, I., Silva, A., Guss, J.M., Mackay, J.P., Matthews, J.M.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[6ptl]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6PTL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6PTL FirstGlance]. <br>
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Description: Structure of the self-association domain of the chromatin looping factor LDB1
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6ptl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ptl OCA], [https://pdbe.org/6ptl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6ptl RCSB], [https://www.ebi.ac.uk/pdbsum/6ptl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6ptl ProSAT]</span></td></tr>
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[[Category: Mackay, J.P]]
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</table>
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[[Category: Guss, J.M]]
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== Function ==
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[[Category: Macindoe, I]]
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[https://www.uniprot.org/uniprot/LDB1_MOUSE LDB1_MOUSE] Binds to the LIM domain of a wide variety of LIM domain-containing transcription factors. May regulate the transcriptional activity of LIM-containing proteins by determining specific partner interactions. May play a role in the development of motor neurons. Acts synergistically with LHX1/LIM1 in axis formation and activation of gene expression. Acts with LMO2 in the regulation of red blood cell development, maintaining erythroid precursors in an immature state.<ref>PMID:8918878</ref> <ref>PMID:8876198</ref> <ref>PMID:9192866</ref> <ref>PMID:9391090</ref> <ref>PMID:16815859</ref> <ref>PMID:9315627</ref>
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[[Category: Matthews, J.M]]
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== References ==
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[[Category: Silva, A]]
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Mus musculus]]
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[[Category: Guss JM]]
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[[Category: Macindoe I]]
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[[Category: Mackay JP]]
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[[Category: Matthews JM]]
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[[Category: Silva A]]

Current revision

Structure of the self-association domain of the chromatin looping factor LDB1

PDB ID 6ptl

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