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6sks
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 6sks is ON HOLD Authors: Groves, M.R., Wang, W., van Oosterwijk, N. Description: Crystal structure of bovine carbonic anhydrase II in complex with ...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of bovine carbonic anhydrase II in complex with a benzenesulfonamide-based ligand (SH1)== | |
| + | <StructureSection load='6sks' size='340' side='right'caption='[[6sks]], [[Resolution|resolution]] 1.75Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[6sks]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6SKS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6SKS FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.75Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=E68:~{N}-[2-[2-(1~{H}-imidazol-4-yl)ethylamino]-2-oxidanylidene-ethyl]-4-sulfamoyl-benzamide'>E68</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6sks FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6sks OCA], [https://pdbe.org/6sks PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6sks RCSB], [https://www.ebi.ac.uk/pdbsum/6sks PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6sks ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/CAH2_BOVIN CAH2_BOVIN] Essential for bone resorption and osteoclast differentiation (By similarity). Reversible hydration of carbon dioxide. | ||
| - | + | ==See Also== | |
| - | + | *[[Carbonic anhydrase 3D structures|Carbonic anhydrase 3D structures]] | |
| - | + | __TOC__ | |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: | + | [[Category: Bos taurus]] |
| - | [[Category: Wang | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Groves MR]] |
| + | [[Category: Wang W]] | ||
| + | [[Category: Van Oosterwijk N]] | ||
Current revision
Crystal structure of bovine carbonic anhydrase II in complex with a benzenesulfonamide-based ligand (SH1)
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