1aun

From Proteopedia

(Difference between revisions)

Current revision

PATHOGENESIS-RELATED PROTEIN 5D FROM NICOTIANA TABACUM

Structural highlights

1aun is a 1 chain structure with sequence from Nicotiana tabacum. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:	X-ray diffraction, Resolution 1.8Å
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

OLPA_TOBAC

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

Publication Abstract from PubMed

The crystal structure of tobacco PR-5d, an antifungal thaumatin-like protein isolated from cultured tobacco cells, was determined at the resolution of 1.8 A. The structure consists of 208 amino acid residues and 89 water molecules with a crystallographic R-factor of 0.169. The model has good stereochemistry, with respective root-mean-square deviations from the ideal values for bond and angle distances of 0.007 A and 1.542 degrees. Of the homologous PR-5 proteins, only those with antifungal activity had a common motif, a negatively charged surface cleft. This cleft is at the boundary between domains I and II, with a bottom part consisting of a three-stranded antiparallel beta-sheet in domain I. The acidic residues located in the hollow of the cleft form the beta-sheet region. Sequence and secondary structure analyses showed that the amino acid residues comprising the acidic cleft of PR-5d are conserved among other antifungal PR-5 proteins. This is the first report on the high-resolution crystal structure of an antifungal PR-5 protein. This structure provides insight into the function of pathogenesis-related proteins.

Crystal structure of tobacco PR-5d protein at 1.8 A resolution reveals a conserved acidic cleft structure in antifungal thaumatin-like proteins.,Koiwa H, Kato H, Nakatsu T, Oda J, Yamada Y, Sato F J Mol Biol. 1999 Mar 5;286(4):1137-45. PMID:10047487^[1]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

References

↑ Koiwa H, Kato H, Nakatsu T, Oda J, Yamada Y, Sato F. Crystal structure of tobacco PR-5d protein at 1.8 A resolution reveals a conserved acidic cleft structure in antifungal thaumatin-like proteins. J Mol Biol. 1999 Mar 5;286(4):1137-45. PMID:10047487 doi:http://dx.doi.org/10.1006/jmbi.1998.2540

1 Structural highlights
2 Function
3 Evolutionary Conservation
4 Publication Abstract from PubMed
5 References

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1aun"

@@ Line 3: / Line 3: @@
 <StructureSection load='1aun' size='340' side='right'caption='[[1aun]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[1aun]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Nicotiana_tabacum Nicotiana tabacum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AUN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1AUN FirstGlance]. <br>
+<table><tr><td colspan='2'>[[1aun]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Nicotiana_tabacum Nicotiana tabacum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AUN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1AUN FirstGlance]. <br>
-</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1aun FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1aun OCA], [http://pdbe.org/1aun PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1aun RCSB], [http://www.ebi.ac.uk/pdbsum/1aun PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1aun ProSAT]</span></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1aun FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1aun OCA], [https://pdbe.org/1aun PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1aun RCSB], [https://www.ebi.ac.uk/pdbsum/1aun PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1aun ProSAT]</span></td></tr>
 </table>
+== Function ==
+[https://www.uniprot.org/uniprot/OLPA_TOBAC OLPA_TOBAC]
 == Evolutionary Conservation ==
 [[Image:Consurf_key_small.gif|200px|right]]
@@ Line 11: / Line 14: @@
   <jmolCheckbox>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/au/1aun_consurf.spt"</scriptWhenChecked>
-    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
@@ Line 31: / Line 34: @@
 [[Category: Large Structures]]
 [[Category: Nicotiana tabacum]]
-[[Category: Kato, H]]
+[[Category: Kato H]]
-[[Category: Koiwa, H]]
+[[Category: Koiwa H]]
-[[Category: Nakatsu, T]]
+[[Category: Nakatsu T]]
-[[Category: Oda, J]]
+[[Category: Oda J]]
-[[Category: Sato, F]]
+[[Category: Sato F]]
-[[Category: Yamada, Y]]
+[[Category: Yamada Y]]
-[[Category: Antifungal protein]]
-[[Category: Osmotin]]
-[[Category: Pathogenesis-related protein]]
-[[Category: Pr-5d]]
-[[Category: Thaumatin-like protein]]

1aun

From Proteopedia

Current revision

PATHOGENESIS-RELATED PROTEIN 5D FROM NICOTIANA TABACUM

Structural highlights

Function

Evolutionary Conservation

Publication Abstract from PubMed

References

Contents

Proteopedia Page Contributors and Editors (what is this?)

Views

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