6kuw
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of human alpha2C adrenergic G protein-coupled receptor.== | |
| + | <StructureSection load='6kuw' size='340' side='right'caption='[[6kuw]], [[Resolution|resolution]] 2.80Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[6kuw]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6KUW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6KUW FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CLR:CHOLESTEROL'>CLR</scene>, <scene name='pdbligand=E33:(8~{a}~{R},12~{a}~{S},13~{a}~{R})-12-ethylsulfonyl-3-methoxy-5,6,8,8~{a},9,10,11,12~{a},13,13~{a}-decahydroisoquinolino[2,1-g][1,6]naphthyridine'>E33</scene>, <scene name='pdbligand=OLA:OLEIC+ACID'>OLA</scene>, <scene name='pdbligand=OLC:(2R)-2,3-DIHYDROXYPROPYL+(9Z)-OCTADEC-9-ENOATE'>OLC</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6kuw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6kuw OCA], [https://pdbe.org/6kuw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6kuw RCSB], [https://www.ebi.ac.uk/pdbsum/6kuw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6kuw ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/ADA2C_HUMAN ADA2C_HUMAN] Alpha-2 adrenergic receptors mediate the catecholamine-induced inhibition of adenylate cyclase through the action of G proteins.[https://www.uniprot.org/uniprot/Q9V2J8_PYRAB Q9V2J8_PYRAB] | ||
| - | + | ==See Also== | |
| - | + | *[[Adrenergic receptor 3D structures|Adrenergic receptor 3D structures]] | |
| - | + | __TOC__ | |
| - | [[Category: | + | </StructureSection> |
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Chen XY]] | ||
| + | [[Category: Wu D]] | ||
| + | [[Category: Wu LJ]] | ||
| + | [[Category: Zhong GS]] | ||
Current revision
Crystal structure of human alpha2C adrenergic G protein-coupled receptor.
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Categories: Homo sapiens | Large Structures | Chen XY | Wu D | Wu LJ | Zhong GS
