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6kw5
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | The | + | ==The ClassC RSC-Nucleosome Complex== |
| + | <StructureSection load='6kw5' size='340' side='right'caption='[[6kw5]], [[Resolution|resolution]] 10.13Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[6kw5]] is a 13 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens], [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C] and [https://en.wikipedia.org/wiki/Xenopus_laevis Xenopus laevis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6KW5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6KW5 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 10.13Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6kw5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6kw5 OCA], [https://pdbe.org/6kw5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6kw5 RCSB], [https://www.ebi.ac.uk/pdbsum/6kw5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6kw5 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/H2A1_XENLA H2A1_XENLA] Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | ||
| - | + | ==See Also== | |
| - | + | *[[Actin-related protein 3D structures|Actin-related protein 3D structures]] | |
| - | + | *[[Helicase 3D structures|Helicase 3D structures]] | |
| - | [[Category: | + | *[[Histone 3D structures|Histone 3D structures]] |
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Saccharomyces cerevisiae S288C]] | ||
| + | [[Category: Xenopus laevis]] | ||
| + | [[Category: Cairns B]] | ||
| + | [[Category: Chen KJ]] | ||
| + | [[Category: Chen ZC]] | ||
| + | [[Category: Gao N]] | ||
| + | [[Category: Verma N]] | ||
| + | [[Category: Wu H]] | ||
| + | [[Category: Ye YP]] | ||
Current revision
The ClassC RSC-Nucleosome Complex
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Categories: Homo sapiens | Large Structures | Saccharomyces cerevisiae S288C | Xenopus laevis | Cairns B | Chen KJ | Chen ZC | Gao N | Verma N | Wu H | Ye YP
