6kyr
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of DCLK1 mutant (P675L) Autoinhibited Kinase Domain== | |
| + | <StructureSection load='6kyr' size='340' side='right'caption='[[6kyr]], [[Resolution|resolution]] 2.21Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[6kyr]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6KYR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6KYR FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.206Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6kyr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6kyr OCA], [https://pdbe.org/6kyr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6kyr RCSB], [https://www.ebi.ac.uk/pdbsum/6kyr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6kyr ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/DCLK1_HUMAN DCLK1_HUMAN] Probable kinase that may be involved in a calcium-signaling pathway controlling neuronal migration in the developing brain. May also participate in functions of the mature nervous system. | ||
| - | + | ==See Also== | |
| - | + | *[[Serine/threonine protein kinase 3D structures|Serine/threonine protein kinase 3D structures]] | |
| - | + | __TOC__ | |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | [[Category: Chen | + | [[Category: Large Structures]] |
| + | [[Category: Chen Q]] | ||
| + | [[Category: Yu Y]] | ||
Current revision
Crystal structure of DCLK1 mutant (P675L) Autoinhibited Kinase Domain
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