6uap

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
m (Protected "6uap" [edit=sysop:move=sysop])
Current revision (09:47, 2 April 2025) (edit) (undo)
 
(One intermediate revision not shown.)
Line 1: Line 1:
-
'''Unreleased structure'''
 
-
The entry 6uap is ON HOLD
+
==Crystal structure of tryptophan synthase from M. tuberculosis - open form with BRD6309 bound==
 +
<StructureSection load='6uap' size='340' side='right'caption='[[6uap]], [[Resolution|resolution]] 2.75&Aring;' scene=''>
 +
== Structural highlights ==
 +
<table><tr><td colspan='2'>[[6uap]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6UAP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6UAP FirstGlance]. <br>
 +
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.745&#8491;</td></tr>
 +
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=H9V:(2~{R},3~{S},4~{R})-3-[4-[4-chloranyl-2,6-bis(fluoranyl)phenyl]phenyl]-4-(fluoranylmethyl)azetidine-2-carbonitrile'>H9V</scene>, <scene name='pdbligand=LLP:(2S)-2-AMINO-6-[[3-HYDROXY-2-METHYL-5-(PHOSPHONOOXYMETHYL)PYRIDIN-4-YL]METHYLIDENEAMINO]HEXANOIC+ACID'>LLP</scene>, <scene name='pdbligand=MLA:MALONIC+ACID'>MLA</scene>, <scene name='pdbligand=MLT:D-MALATE'>MLT</scene></td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6uap FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6uap OCA], [https://pdbe.org/6uap PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6uap RCSB], [https://www.ebi.ac.uk/pdbsum/6uap PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6uap ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/TRPA_MYCTU TRPA_MYCTU] The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
-
Authors: Chang, C., Michalska, K., Maltseva, N.I., Jedrzejczak, R., McCarren, P., Nag, P.P., Joachimiak, A., Satchell, K., Center for Structural Genomics of Infectious Diseases (CSGID)
+
==See Also==
-
 
+
*[[Tryptophan synthase 3D structures|Tryptophan synthase 3D structures]]
-
Description: Crystal structure of tryptophan synthase from M. tuberculosis -open form with BRD6309 bound
+
__TOC__
-
[[Category: Unreleased Structures]]
+
</StructureSection>
-
[[Category: Michalska, K]]
+
[[Category: Large Structures]]
-
[[Category: Mccarren, P]]
+
[[Category: Mycobacterium tuberculosis H37Rv]]
-
[[Category: Joachimiak, A]]
+
[[Category: Chang C]]
-
[[Category: Maltseva, N.I]]
+
[[Category: Jedrzejczak R]]
-
[[Category: Satchell, K]]
+
[[Category: Joachimiak A]]
-
[[Category: Jedrzejczak, R]]
+
[[Category: Maltseva NI]]
-
[[Category: Center For Structural Genomics Of Infectious Diseases (Csgid)]]
+
[[Category: McCarren P]]
-
[[Category: Chang, C]]
+
[[Category: Michalska K]]
-
[[Category: Nag, P.P]]
+
[[Category: Nag PP]]
 +
[[Category: Satchell K]]

Current revision

Crystal structure of tryptophan synthase from M. tuberculosis - open form with BRD6309 bound

PDB ID 6uap

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/6uap"
Personal tools