4c5a

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<StructureSection load='4c5a' size='340' side='right'caption='[[4c5a]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
<StructureSection load='4c5a' size='340' side='right'caption='[[4c5a]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4c5a]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4C5A OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4C5A FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4c5a]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4C5A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4C5A FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=DS0:[(4R)-4-AZANYL-4,5-DIHYDRO-1,2-OXAZOL-3-YL]+DIHYDROGEN+PHOSPHATE'>DS0</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.65&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4c5b|4c5b]], [[4c5c|4c5c]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=DS0:[(4R)-4-AZANYL-4,5-DIHYDRO-1,2-OXAZOL-3-YL]+DIHYDROGEN+PHOSPHATE'>DS0</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/D-alanine--D-alanine_ligase D-alanine--D-alanine ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.3.2.4 6.3.2.4] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4c5a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4c5a OCA], [https://pdbe.org/4c5a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4c5a RCSB], [https://www.ebi.ac.uk/pdbsum/4c5a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4c5a ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4c5a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4c5a OCA], [http://pdbe.org/4c5a PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4c5a RCSB], [http://www.ebi.ac.uk/pdbsum/4c5a PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4c5a ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/C4ZRI7_ECOBW C4ZRI7_ECOBW]] Cell wall formation.[HAMAP-Rule:MF_00047][SAAS:SAAS00058712]
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[https://www.uniprot.org/uniprot/DDLB_ECOLI DDLB_ECOLI] Cell wall formation.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: D-alanine--D-alanine ligase]]
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[[Category: Escherichia coli K-12]]
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[[Category: Ecoli]]
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[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Batson, S]]
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[[Category: Synthetic construct]]
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[[Category: Fishwick, C W.G]]
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[[Category: Batson S]]
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[[Category: Fulop, V]]
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[[Category: Fishwick CWG]]
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[[Category: Lloyd, A J]]
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[[Category: Fulop V]]
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[[Category: Majce, V]]
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[[Category: Lloyd AJ]]
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[[Category: Rea, D]]
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[[Category: Majce V]]
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[[Category: Roper, D I]]
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[[Category: Rea D]]
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[[Category: Simmons, K J]]
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[[Category: Roper DI]]
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[[Category: Antibiotic]]
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[[Category: Simmons KJ]]
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[[Category: Ddlb]]
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[[Category: Ligase]]
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Current revision

The X-ray crystal structures of D-alanyl-D-alanine ligase in complex ADP and D-cycloserine phosphate

PDB ID 4c5a

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