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| | <StructureSection load='6qxv' size='340' side='right'caption='[[6qxv]], [[Resolution|resolution]] 1.94Å' scene=''> | | <StructureSection load='6qxv' size='340' side='right'caption='[[6qxv]], [[Resolution|resolution]] 1.94Å' scene=''> |
| | == Structural highlights == | | == Structural highlights == |
| - | <table><tr><td colspan='2'>[[6qxv]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Beauveria_alba Beauveria alba]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6QXV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6QXV FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[6qxv]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Parengyodontium_album Parengyodontium album]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6QXV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6QXV FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.94Å</td></tr> |
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PROK ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=37998 Beauveria alba])</td></tr> | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> |
| - | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Peptidase_K Peptidase K], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.64 3.4.21.64] </span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6qxv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6qxv OCA], [https://pdbe.org/6qxv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6qxv RCSB], [https://www.ebi.ac.uk/pdbsum/6qxv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6qxv ProSAT]</span></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6qxv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6qxv OCA], [http://pdbe.org/6qxv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6qxv RCSB], [http://www.ebi.ac.uk/pdbsum/6qxv PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6qxv ProSAT]</span></td></tr> | + | |
| | </table> | | </table> |
| | == Function == | | == Function == |
| - | [[http://www.uniprot.org/uniprot/PRTK_PARAQ PRTK_PARAQ]] Hydrolyzes keratin at aromatic and hydrophobic residues. | + | [https://www.uniprot.org/uniprot/PRTK_PARAQ PRTK_PARAQ] Hydrolyzes keratin at aromatic and hydrophobic residues. |
| | <div style="background-color:#fffaf0;"> | | <div style="background-color:#fffaf0;"> |
| | == Publication Abstract from PubMed == | | == Publication Abstract from PubMed == |
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| | </div> | | </div> |
| | <div class="pdbe-citations 6qxv" style="background-color:#fffaf0;"></div> | | <div class="pdbe-citations 6qxv" style="background-color:#fffaf0;"></div> |
| | + | |
| | + | ==See Also== |
| | + | *[[Proteinase 3D structures|Proteinase 3D structures]] |
| | == References == | | == References == |
| | <references/> | | <references/> |
| | __TOC__ | | __TOC__ |
| | </StructureSection> | | </StructureSection> |
| - | [[Category: Beauveria alba]] | |
| | [[Category: Large Structures]] | | [[Category: Large Structures]] |
| - | [[Category: Peptidase K]] | + | [[Category: Parengyodontium album]] |
| - | [[Category: Meents, A]] | + | [[Category: Meents A]] |
| - | [[Category: Oberthuer, D]] | + | [[Category: Oberthuer D]] |
| - | [[Category: Tolstikova, A]] | + | [[Category: Tolstikova A]] |
| - | [[Category: Fixed-target]]
| + | |
| - | [[Category: Hydrolase]]
| + | |
| - | [[Category: Pink beam]]
| + | |
| - | [[Category: Proteinase k]]
| + | |
| - | [[Category: Serial crystallography]]
| + | |
| Structural highlights
Function
PRTK_PARAQ Hydrolyzes keratin at aromatic and hydrophobic residues.
Publication Abstract from PubMed
Reliable sample delivery and efficient use of limited beam time have remained bottlenecks for serial crystallography (SX). Using a high-intensity polychromatic X-ray beam in combination with a newly developed charge-integrating JUNGFRAU detector, we have applied the method of fixed-target SX to collect data at a rate of 1 kHz at a synchrotron-radiation facility. According to our data analysis for the given experimental conditions, only about 3 000 diffraction patterns are required for a high-quality diffraction dataset. With indexing rates of up to 25%, recording of such a dataset takes less than 30 s.
1 kHz fixed-target serial crystallography using a multilayer monochromator and an integrating pixel detector.,Tolstikova A, Levantino M, Yefanov O, Hennicke V, Fischer P, Meyer J, Mozzanica A, Redford S, Crosas E, Opara NL, Barthelmess M, Lieske J, Oberthuer D, Wator E, Mohacsi I, Wulff M, Schmitt B, Chapman HN, Meents A IUCrJ. 2019 Aug 17;6(Pt 5):927-937. doi: 10.1107/S205225251900914X. eCollection, 2019 Sep 1. PMID:31576225[1]
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.
See Also
References
- ↑ Tolstikova A, Levantino M, Yefanov O, Hennicke V, Fischer P, Meyer J, Mozzanica A, Redford S, Crosas E, Opara NL, Barthelmess M, Lieske J, Oberthuer D, Wator E, Mohacsi I, Wulff M, Schmitt B, Chapman HN, Meents A. 1 kHz fixed-target serial crystallography using a multilayer monochromator and an integrating pixel detector. IUCrJ. 2019 Aug 17;6(Pt 5):927-937. doi: 10.1107/S205225251900914X. eCollection, 2019 Sep 1. PMID:31576225 doi:http://dx.doi.org/10.1107/S205225251900914X
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