This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
6ul7
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 6ul7 is ON HOLD until Paper Publication Authors: Description: Category: Unreleased Structures) |
|||
| (2 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Structure of human ketohexokinase-C in complex with fructose, NO3, and osthole== | |
| + | <StructureSection load='6ul7' size='340' side='right'caption='[[6ul7]], [[Resolution|resolution]] 2.30Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[6ul7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6UL7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6UL7 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A0O:7-methoxy-8-(3-methylbut-2-enyl)chromen-2-one'>A0O</scene>, <scene name='pdbligand=FRU:FRUCTOSE'>FRU</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6ul7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ul7 OCA], [https://pdbe.org/6ul7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6ul7 RCSB], [https://www.ebi.ac.uk/pdbsum/6ul7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6ul7 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Disease == | ||
| + | [https://www.uniprot.org/uniprot/KHK_HUMAN KHK_HUMAN] Defects in KHK are the cause of fructosuria (FRUCT) [MIM:[https://omim.org/entry/229800 229800]. Benign defect of intermediary metabolism.<ref>PMID:19237742</ref> <ref>PMID:7833921</ref> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/KHK_HUMAN KHK_HUMAN] | ||
| - | + | ==See Also== | |
| - | + | *[[Ketohexokinase|Ketohexokinase]] | |
| - | + | == References == | |
| - | [[Category: | + | <references/> |
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Allen KN]] | ||
| + | [[Category: Gardner S]] | ||
| + | [[Category: Gasper WC]] | ||
| + | [[Category: Tolan DR]] | ||
Current revision
Structure of human ketohexokinase-C in complex with fructose, NO3, and osthole
| |||||||||||
