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Vpu protein

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Current revision (10:18, 25 January 2021) (edit) (undo)
 
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[[2n28]] – Vpu - HIV-1 - NMR<br />
[[2n28]] – Vpu - HIV-1 - NMR<br />
-
[[1pi7]], [[1pi8]], [[1pje]], [[2gof]], [[2goh]] – Vpu trans-membrane domain - NMR<br />
+
[[1pi7]], [[1pi8]], [[1pje]], [[2gof]], [[2goh]], [[2jpx]] – Vpu trans-membrane domain - NMR<br />
-
[[1vpu]], [[2n29]], [[2k7y]] – Vpu cytoplasmic domain - NMR<br />
+
[[1vpu]], [[2n28]], [[2n29]], [[2k7y]] – Vpu cytoplasmic domain - NMR<br />
[[4p6z]] – Vpu cytoplasmic domain + BST2 + AP-1 core<br />
[[4p6z]] – Vpu cytoplasmic domain + BST2 + AP-1 core<br />

Current revision

HIV-1 Vpu protein (dark olive) complex with adapter-related protein complex 1 subunits γ-1 (gold), σ-1a (khaki), μ-1 (olive green), β-1 (green) (PDB code 4p6z)

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3D Structures of Vpu protein

Updated on 25-January-2021

2n28 – Vpu - HIV-1 - NMR
1pi7, 1pi8, 1pje, 2gof, 2goh, 2jpx – Vpu trans-membrane domain - NMR
1vpu, 2n28, 2n29, 2k7y – Vpu cytoplasmic domain - NMR
4p6z – Vpu cytoplasmic domain + BST2 + AP-1 core

References

  1. Gonzalez ME. Vpu Protein: The Viroporin Encoded by HIV-1. Viruses. 2015 Aug 4;7(8):4352-68. doi: 10.3390/v7082824. PMID:26247957 doi:http://dx.doi.org/10.3390/v7082824
  2. Bour S, Strebel K. The HIV-1 Vpu protein: a multifunctional enhancer of viral particle release. Microbes Infect. 2003 Sep;5(11):1029-39. PMID:12941395

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Michal Harel, Joel L. Sussman, Alexander Berchansky

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