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6l6z
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Cryo-EM structure of the Drosophila CTP synthase substrate-bound filament== | |
| - | + | <StructureSection load='6l6z' size='340' side='right'caption='[[6l6z]], [[Resolution|resolution]] 6.09Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6l6z]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6L6Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6L6Z FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 6.09Å</td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6l6z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6l6z OCA], [https://pdbe.org/6l6z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6l6z RCSB], [https://www.ebi.ac.uk/pdbsum/6l6z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6l6z ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/PYRG_DROME PYRG_DROME] Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Constitutes the rate-limiting enzyme in the synthesis of cytosine nucleotides (By similarity). Isoform 1 is required for cytoophidium assembly in female germline cells.<ref>PMID:23459760</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Drosophila melanogaster]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Chen-Jun G]] | ||
| + | [[Category: Ji-Long L]] | ||
| + | [[Category: Xian Z]] | ||
Current revision
Cryo-EM structure of the Drosophila CTP synthase substrate-bound filament
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