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6ov1
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Structure of Staphylococcus aureus RNase P protein mutant with defective mRNA degradation activity== | |
| + | <StructureSection load='6ov1' size='340' side='right'caption='[[6ov1]], [[Resolution|resolution]] 1.66Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[6ov1]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6OV1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6OV1 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.66Å</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6ov1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ov1 OCA], [https://pdbe.org/6ov1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6ov1 RCSB], [https://www.ebi.ac.uk/pdbsum/6ov1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6ov1 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/RNPA_STAAU RNPA_STAAU] RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. | ||
| - | + | ==See Also== | |
| - | + | *[[Ribonuclease 3D structures|Ribonuclease 3D structures]] | |
| - | + | __TOC__ | |
| - | [[Category: | + | </StructureSection> |
| + | [[Category: Large Structures]] | ||
| + | [[Category: Staphylococcus aureus]] | ||
| + | [[Category: Colquhoun J]] | ||
| + | [[Category: Das C]] | ||
| + | [[Category: Dunman P]] | ||
| + | [[Category: Flaherty DP]] | ||
| + | [[Category: Ha L]] | ||
| + | [[Category: Noinaj N]] | ||
Current revision
Structure of Staphylococcus aureus RNase P protein mutant with defective mRNA degradation activity
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