5gqh
From Proteopedia
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==Cryo-EM structure of PaeCas3-AcrF3 complex== | ==Cryo-EM structure of PaeCas3-AcrF3 complex== | ||
| - | < | + | <SX load='5gqh' size='340' side='right' viewer='molstar' caption='[[5gqh]], [[Resolution|resolution]] 4.20Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5gqh]] is a 3 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[5gqh]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_UCBPP-PA14 Pseudomonas aeruginosa UCBPP-PA14] and [https://en.wikipedia.org/wiki/Pseudomonas_phage_JBD5 Pseudomonas phage JBD5]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5GQH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5GQH FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 4.2Å</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5gqh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5gqh OCA], [https://pdbe.org/5gqh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5gqh RCSB], [https://www.ebi.ac.uk/pdbsum/5gqh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5gqh ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/CAS3_PSEAB CAS3_PSEAB] CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Cas3 plus Cascade participate in CRISPR interference, the third stage of CRISPR immunity (Potential). In this bacteria Y.pestis-subtype CRISPRs do not confer resistance to phage DSM3 or MP22, but instead are required for DMS3-dependent inhibition of biofilm formation and possibly motility.<ref>PMID:21398535</ref> |
==See Also== | ==See Also== | ||
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<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
| - | </ | + | </SX> |
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: | + | [[Category: Pseudomonas aeruginosa UCBPP-PA14]] |
| - | [[Category: Pseudomonas phage | + | [[Category: Pseudomonas phage JBD5]] |
| - | [[Category: Ma | + | [[Category: Ma J]] |
| - | [[Category: Wang | + | [[Category: Wang J]] |
| - | [[Category: Wang | + | [[Category: Wang Y]] |
| - | [[Category: Zhang | + | [[Category: Zhang X]] |
| - | + | ||
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Current revision
Cryo-EM structure of PaeCas3-AcrF3 complex
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