6l8z
From Proteopedia
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- | '''Unreleased structure''' | ||
- | + | ==Crystal structure of ugt transferase mutant in complex with UPG== | |
+ | <StructureSection load='6l8z' size='340' side='right'caption='[[6l8z]], [[Resolution|resolution]] 2.10Å' scene=''> | ||
+ | == Structural highlights == | ||
+ | <table><tr><td colspan='2'>[[6l8z]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Siraitia_grosvenorii Siraitia grosvenorii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6L8Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6L8Z FirstGlance]. <br> | ||
+ | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1Å</td></tr> | ||
+ | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=UPG:URIDINE-5-DIPHOSPHATE-GLUCOSE'>UPG</scene></td></tr> | ||
+ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6l8z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6l8z OCA], [https://pdbe.org/6l8z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6l8z RCSB], [https://www.ebi.ac.uk/pdbsum/6l8z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6l8z ProSAT]</span></td></tr> | ||
+ | </table> | ||
+ | == Function == | ||
+ | [https://www.uniprot.org/uniprot/74AC1_SIRGR 74AC1_SIRGR] Catalyzes the transfer of a glucose moiety to the C-3 hydroxyl of mogrol to form mogroside IE (PubMed:25759326, Ref.3). Besides mogrol, UGT74AC1 also shows activity in vitro with quercetin and naringenin as substrate (PubMed:25759326).<ref>PMID:25759326</ref> <ref>PMID:25759326</ref> | ||
- | + | ==See Also== | |
- | + | *[[Glycosyltransferase 3D structures|Glycosyltransferase 3D structures]] | |
- | + | == References == | |
- | [[Category: | + | <references/> |
+ | __TOC__ | ||
+ | </StructureSection> | ||
+ | [[Category: Large Structures]] | ||
+ | [[Category: Siraitia grosvenorii]] | ||
+ | [[Category: Li J]] | ||
+ | [[Category: Liu WD]] | ||
+ | [[Category: Shan N]] | ||
+ | [[Category: Sun YX]] | ||
+ | [[Category: Yang JG]] |
Current revision
Crystal structure of ugt transferase mutant in complex with UPG
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Categories: Large Structures | Siraitia grosvenorii | Li J | Liu WD | Shan N | Sun YX | Yang JG