6qb6

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Current revision (08:15, 17 October 2024) (edit) (undo)
 
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<StructureSection load='6qb6' size='340' side='right'caption='[[6qb6]], [[Resolution|resolution]] 2.24&Aring;' scene=''>
<StructureSection load='6qb6' size='340' side='right'caption='[[6qb6]], [[Resolution|resolution]] 2.24&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6qb6]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6QB6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6QB6 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6qb6]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6QB6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6QB6 FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6qb3|6qb3]], [[6qb4|6qb4]], [[6fs0|6fs0]]</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.24&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MCL1, BCL2L3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6qb6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6qb6 OCA], [https://pdbe.org/6qb6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6qb6 RCSB], [https://www.ebi.ac.uk/pdbsum/6qb6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6qb6 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6qb6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6qb6 OCA], [http://pdbe.org/6qb6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6qb6 RCSB], [http://www.ebi.ac.uk/pdbsum/6qb6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6qb6 ProSAT]</span></td></tr>
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</table>
</table>
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== Function ==
 
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[[http://www.uniprot.org/uniprot/MCL1_HUMAN MCL1_HUMAN]] Involved in the regulation of apoptosis versus cell survival, and in the maintenance of viability but not of proliferation. Mediates its effects by interactions with a number of other regulators of apoptosis. Isoform 1 inhibits apoptosis. Isoform 2 promotes apoptosis.<ref>PMID:10766760</ref>
 
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 6qb6" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 6qb6" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[B-cell lymphoma proteins 3D structures|B-cell lymphoma proteins 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Hargreaves, D]]
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[[Category: Hargreaves D]]
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[[Category: Apoptosis]]
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[[Category: Azd5991]]
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[[Category: Fab]]
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[[Category: Mcl1]]
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Current revision

Mcl1 in complex with a Fab

PDB ID 6qb6

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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