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6mfy

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<StructureSection load='6mfy' size='340' side='right'caption='[[6mfy]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
<StructureSection load='6mfy' size='340' side='right'caption='[[6mfy]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6mfy]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6MFY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6MFY FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6mfy]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Brevibacillus_parabrevis Brevibacillus parabrevis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6MFY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6MFY FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PNS:4-PHOSPHOPANTETHEINE'>PNS</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6mfy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6mfy OCA], [http://pdbe.org/6mfy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6mfy RCSB], [http://www.ebi.ac.uk/pdbsum/6mfy PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6mfy ProSAT]</span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PNS:4-PHOSPHOPANTETHEINE'>PNS</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6mfy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6mfy OCA], [https://pdbe.org/6mfy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6mfy RCSB], [https://www.ebi.ac.uk/pdbsum/6mfy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6mfy ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/LGRA_BREPA LGRA_BREPA]] Activates valine (or leucine, but much less frequently), and then glycine and catalyzes the formation of the peptide bond in the first step of peptide synthesis. This enzyme may also play a role in N-formylation of the first amino acid residue in the synthesized dipeptide.
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[https://www.uniprot.org/uniprot/LGRA_BREPA LGRA_BREPA] Activates valine (or leucine, but much less frequently), and then glycine and catalyzes the formation of the peptide bond in the first step of peptide synthesis. This enzyme may also play a role in N-formylation of the first amino acid residue in the synthesized dipeptide.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 6mfy" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 6mfy" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Linear gramicidin synthase|Linear gramicidin synthase]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Brevibacillus parabrevis]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Eivaskhani, M]]
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[[Category: Eivaskhani M]]
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[[Category: Harb, I]]
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[[Category: Harb I]]
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[[Category: Reimer, J M]]
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[[Category: Reimer JM]]
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[[Category: Schmeing, T M]]
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[[Category: Schmeing TM]]
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[[Category: Enzyme]]
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[[Category: Ligase]]
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[[Category: Linear gramicidin]]
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[[Category: Natural product]]
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[[Category: Nonribosomal peptide synthetase]]
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[[Category: Nrp]]
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[[Category: Tailoring domain]]
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Current revision

Crystal structure of a 5-domain construct of LgrA in the substrate donation state

PDB ID 6mfy

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