6mfz

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<StructureSection load='6mfz' size='340' side='right'caption='[[6mfz]], [[Resolution|resolution]] 6.00&Aring;' scene=''>
<StructureSection load='6mfz' size='340' side='right'caption='[[6mfz]], [[Resolution|resolution]] 6.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6mfz]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6MFZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6MFZ FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6mfz]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Brevibacillus_parabrevis Brevibacillus parabrevis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6MFZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6MFZ FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PNS:4-PHOSPHOPANTETHEINE'>PNS</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 6&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6mfz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6mfz OCA], [http://pdbe.org/6mfz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6mfz RCSB], [http://www.ebi.ac.uk/pdbsum/6mfz PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6mfz ProSAT]</span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PNS:4-PHOSPHOPANTETHEINE'>PNS</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6mfz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6mfz OCA], [https://pdbe.org/6mfz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6mfz RCSB], [https://www.ebi.ac.uk/pdbsum/6mfz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6mfz ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/LGRA_BREPA LGRA_BREPA]] Activates valine (or leucine, but much less frequently), and then glycine and catalyzes the formation of the peptide bond in the first step of peptide synthesis. This enzyme may also play a role in N-formylation of the first amino acid residue in the synthesized dipeptide.
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[https://www.uniprot.org/uniprot/LGRA_BREPA LGRA_BREPA] Activates valine (or leucine, but much less frequently), and then glycine and catalyzes the formation of the peptide bond in the first step of peptide synthesis. This enzyme may also play a role in N-formylation of the first amino acid residue in the synthesized dipeptide.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 6mfz" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 6mfz" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Linear gramicidin synthase|Linear gramicidin synthase]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Brevibacillus parabrevis]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Eivaskhani, M]]
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[[Category: Eivaskhani M]]
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[[Category: Harb, I]]
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[[Category: Harb I]]
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[[Category: Reimer, J M]]
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[[Category: Reimer JM]]
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[[Category: Schmeing, T M]]
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[[Category: Schmeing TM]]
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[[Category: Enzyme]]
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[[Category: Ligase]]
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[[Category: Linear gramicidin]]
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[[Category: Natural product]]
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[[Category: Nonribosomal peptide synthetase]]
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[[Category: Nrp]]
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[[Category: Tailoring domain]]
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Current revision

Crystal structure of dimodular LgrA in a condensation state

PDB ID 6mfz

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