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6o8d

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Current revision (07:06, 11 October 2023) (edit) (undo)
 
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<StructureSection load='6o8d' size='340' side='right'caption='[[6o8d]], [[Resolution|resolution]] 3.55&Aring;' scene=''>
<StructureSection load='6o8d' size='340' side='right'caption='[[6o8d]], [[Resolution|resolution]] 3.55&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6o8d]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6O8D OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6O8D FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6o8d]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6O8D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6O8D FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.547&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6o8d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6o8d OCA], [http://pdbe.org/6o8d PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6o8d RCSB], [http://www.ebi.ac.uk/pdbsum/6o8d PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6o8d ProSAT]</span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6o8d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6o8d OCA], [https://pdbe.org/6o8d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6o8d RCSB], [https://www.ebi.ac.uk/pdbsum/6o8d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6o8d ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/CD28_HUMAN CD28_HUMAN]] Involved in T-cell activation, the induction of cell proliferation and cytokine production and promotion of T-cell survival.
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[https://www.uniprot.org/uniprot/CD28_HUMAN CD28_HUMAN] Involved in T-cell activation, the induction of cell proliferation and cytokine production and promotion of T-cell survival.
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Lord, D M]]
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[[Category: Lord DM]]
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[[Category: Wei, R R]]
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[[Category: Wei RR]]
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[[Category: Bispecific property]]
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[[Category: Codv]]
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[[Category: Cross-over dual variable immunoglobin]]
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[[Category: Immune system]]
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[[Category: Multifunctional biotherapeutic format]]
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[[Category: Multispecific antibody]]
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[[Category: T cell activation]]
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Current revision

Anti-CD28xCD3 CODV Fab bound to CD28

PDB ID 6o8d

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