1ncv
From Proteopedia
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==DETERMINATION CC-CHEMOKINE MCP-3, NMR, 7 STRUCTURES== | ==DETERMINATION CC-CHEMOKINE MCP-3, NMR, 7 STRUCTURES== | ||
- | <StructureSection load='1ncv' size='340' side='right'caption='[[1ncv | + | <StructureSection load='1ncv' size='340' side='right'caption='[[1ncv]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
- | <table><tr><td colspan='2'>[[1ncv]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[1ncv]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NCV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1NCV FirstGlance]. <br> |
- | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR, 7 models</td></tr> |
+ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ncv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ncv OCA], [https://pdbe.org/1ncv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ncv RCSB], [https://www.ebi.ac.uk/pdbsum/1ncv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ncv ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
- | [ | + | [https://www.uniprot.org/uniprot/CCL7_HUMAN CCL7_HUMAN] Chemotactic factor that attracts monocytes and eosinophils, but not neutrophils. Augments monocyte anti-tumor activity. Also induces the release of gelatinase B. This protein can bind heparin. Binds to CCR1, CCR2 and CCR3. |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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<jmolCheckbox> | <jmolCheckbox> | ||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nc/1ncv_consurf.spt"</scriptWhenChecked> | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nc/1ncv_consurf.spt"</scriptWhenChecked> | ||
- | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/ | + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked> |
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
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==See Also== | ==See Also== | ||
*[[Monocyte chemoattractant protein|Monocyte chemoattractant protein]] | *[[Monocyte chemoattractant protein|Monocyte chemoattractant protein]] | ||
- | *[[User:Coline Perrin/CCL2|User:Coline Perrin/CCL2]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
- | [[Category: | + | [[Category: Homo sapiens]] |
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
- | [[Category: Bernassau | + | [[Category: Bernassau JM]] |
- | [[Category: Darbon | + | [[Category: Darbon H]] |
- | [[Category: Ferrara | + | [[Category: Ferrara P]] |
- | [[Category: Guillemot | + | [[Category: Guillemot JC]] |
- | [[Category: Meunier | + | [[Category: Meunier S]] |
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Current revision
DETERMINATION CC-CHEMOKINE MCP-3, NMR, 7 STRUCTURES
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