1ntx

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==SECONDARY STRUCTURE DETERMINATION FOR ALPHA-NEUROTOXIN FROM DENDROASPIS POLYLEPIS POLYLEPIS BASED ON SEQUENCE SPECIFIC PROTON NUCLEAR MAGNETIC RESONANCE ASSIGNMENTS==
==SECONDARY STRUCTURE DETERMINATION FOR ALPHA-NEUROTOXIN FROM DENDROASPIS POLYLEPIS POLYLEPIS BASED ON SEQUENCE SPECIFIC PROTON NUCLEAR MAGNETIC RESONANCE ASSIGNMENTS==
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<StructureSection load='1ntx' size='340' side='right'caption='[[1ntx]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
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<StructureSection load='1ntx' size='340' side='right'caption='[[1ntx]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1ntx]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Black_mamba Black mamba]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NTX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1NTX FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1ntx]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Dendroaspis_polylepis_polylepis Dendroaspis polylepis polylepis]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NTX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1NTX FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ntx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ntx OCA], [http://pdbe.org/1ntx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1ntx RCSB], [http://www.ebi.ac.uk/pdbsum/1ntx PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1ntx ProSAT]</span></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR, 20 models</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ntx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ntx OCA], [https://pdbe.org/1ntx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ntx RCSB], [https://www.ebi.ac.uk/pdbsum/1ntx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ntx ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/NXS1_DENPO NXS1_DENPO]] Produces peripheral paralysis by blocking neuromuscular transmission at the postsynaptic site. Binds to the muscular nicotinic acetylcholine receptor.
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[https://www.uniprot.org/uniprot/3S11_DENPO 3S11_DENPO] Binds to muscle nicotinic acetylcholine receptor (nAChR) and inhibit acetylcholine from binding to the receptor, thereby impairing neuromuscular transmission.[UniProtKB:P60775]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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<jmolCheckbox>
<jmolCheckbox>
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nt/1ntx_consurf.spt"</scriptWhenChecked>
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nt/1ntx_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Black mamba]]
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[[Category: Dendroaspis polylepis polylepis]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Brown, L R]]
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[[Category: Brown LR]]
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[[Category: Wuthrich, K]]
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[[Category: Wuthrich K]]
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[[Category: Neurotoxin]]
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Current revision

SECONDARY STRUCTURE DETERMINATION FOR ALPHA-NEUROTOXIN FROM DENDROASPIS POLYLEPIS POLYLEPIS BASED ON SEQUENCE SPECIFIC PROTON NUCLEAR MAGNETIC RESONANCE ASSIGNMENTS

PDB ID 1ntx

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