Poly (ADP-ribose) glycohydrolase
From Proteopedia
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| - | == 3D Structures of poly (ADP-ribose) glycohydrolase == | ||
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| - | Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | ||
| - | {{#tree:id=OrganizedByTopic|openlevels=0| | ||
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| - | *Poly (ADP-ribose) glycohydrolase;Domains: Arh3 19-363; catalytic 448-976 | ||
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| - | **[[4a0d]], [[4b1g]] – hPARG catalytic domain (mutant) - human<br /> | ||
| - | **[[5zqy]] – hPARG Arh3 residues 19-363 <br /> | ||
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| - | **[[3uek]] – rPARG catalytic domain - rat<br /> | ||
| - | **[[4fc2]] – mPARG catalytic domain - mouse<br /> | ||
| - | **[[4n9y]], [[4n9z]], [[4na5]], [[4na6]] – mPARG catalytic domain (mutant) <br /> | ||
| - | **[[2qty]] – mPARG 3 <br /> | ||
| - | **[[3sih]] – TcPARG – ''Thermonospora curvata''<br /> | ||
| - | **[[3sij]] – TcPARG (mutant) <br /> | ||
| - | **[[5zda]] – DrPARG – ''Deinococcus radiodurans''<br /> | ||
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| - | *Poly (ADP-ribose) glycohydrolase complex with ADP-ribose | ||
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| - | **[[4b1h]] – hPARG catalytic domain (mutant) + ADP-ribose<br /> | ||
| - | **[[6d36]] – hPARG Arh3 residues 1-363 + ADP-ribose<br /> | ||
| - | **[[6d3a]] – hPARG Arh3 residues 1-363 (mutant) + ADP-ribose<br /> | ||
| - | **[[4na0]] – mPARG catalytic domain + ADP-ribose<br /> | ||
| - | **[[3sig]] – TcPARG + ADP-ribose <br /> | ||
| - | **[[4epp]] – TtPARG + ADP-ribose - ''Tetrahymena thermophila'' <br /> | ||
| - | **[[4l2h]], [[5a7r]] – TtPARG (mutant) + ADP-ribose <br /> | ||
| - | **[[5zdb]], [[5zdc]], [[5zdd]], [[5zde]] – DrPARG + ADP-ribose <br /> | ||
| - | **[[5zdf]] – DrPARG (mutant) + ADP-ribose <br /> | ||
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| - | * Poly (ADP-ribose) glycohydrolase complex with inhibitor | ||
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| - | **[[4b1i]], [[4b1j]], [[5lhb]], [[6hmk]], [[6hml]], [[6hmm]], [[6hmn]] – hPARG catalytic domain (mutant) + inhibitor<br /> | ||
| - | **[[3uel]] – rPARG catalytic domain + inhibitor <br /> | ||
| - | **[[4na4]] – mPARG catalytic domain + inhibitor <br /> | ||
| - | **[[3sii]] – TcPARG + inhibitor <br /> | ||
| - | **[[4epq]] – TtPARG + inhibitor <br /> | ||
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| - | }} | ||
== References == | == References == | ||
Current revision
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References
- ↑ Herceg Z, Wang ZQ. Functions of poly(ADP-ribose) polymerase (PARP) in DNA repair, genomic integrity and cell death. Mutat Res. 2001 Jun 2;477(1-2):97-110. PMID:11376691
- ↑ Virag L, Szabo C. The therapeutic potential of poly(ADP-ribose) polymerase inhibitors. Pharmacol Rev. 2002 Sep;54(3):375-429. PMID:12223530
- ↑ Slade D, Dunstan MS, Barkauskaite E, Weston R, Lafite P, Dixon N, Ahel M, Leys D, Ahel I. The structure and catalytic mechanism of a poly(ADP-ribose) glycohydrolase. Nature. 2011 Sep 4. doi: 10.1038/nature10404. PMID:21892188 doi:10.1038/nature10404
