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6tgs

From Proteopedia

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'''Unreleased structure'''
 
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The entry 6tgs is ON HOLD
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==AtNBR1-PB1 domain==
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<StructureSection load='6tgs' size='340' side='right'caption='[[6tgs]], [[Resolution|resolution]] 1.53&Aring;' scene=''>
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Authors: Jakobi, A.J., Sachse, C.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[6tgs]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6TGS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6TGS FirstGlance]. <br>
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Description: AtNBR1-PB1 domain
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.53&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=SIN:SUCCINIC+ACID'>SIN</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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[[Category: Jakobi, A.J]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6tgs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6tgs OCA], [https://pdbe.org/6tgs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6tgs RCSB], [https://www.ebi.ac.uk/pdbsum/6tgs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6tgs ProSAT]</span></td></tr>
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[[Category: Sachse, C]]
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/NBR1_ARATH NBR1_ARATH] Autophagic substrate degraded in the vacuole by non-selective autophagy. Requires ATG8 protein expression to be recognized as an autophagic substrate (PubMed:21606687). Acts probably as a receptor for autophagosomal degradation of ubiquitinated proteins. Targets ubiquitinated protein aggregates derived from denatured or damaged non-native proteins generated under stress conditions (PubMed:23341779). Functions additively with the E3 ubiquitin-protein ligase CHIP for autophagosomal degradation of proteotoxic aggregates formed under stress conditions (PubMed:24497840).<ref>PMID:21606687</ref> <ref>PMID:23341779</ref> <ref>PMID:24497840</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Arabidopsis thaliana]]
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[[Category: Large Structures]]
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[[Category: Jakobi AJ]]
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[[Category: Sachse C]]

Current revision

AtNBR1-PB1 domain

PDB ID 6tgs

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