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5i7m

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Current revision (08:25, 23 August 2023) (edit) (undo)
 
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<StructureSection load='5i7m' size='340' side='right'caption='[[5i7m]], [[Resolution|resolution]] 1.93&Aring;' scene=''>
<StructureSection load='5i7m' size='340' side='right'caption='[[5i7m]], [[Resolution|resolution]] 1.93&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5i7m]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5I7M OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5I7M FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5i7m]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5I7M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5I7M FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.93&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PRIM2, PRIM2A ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5i7m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5i7m OCA], [http://pdbe.org/5i7m PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5i7m RCSB], [http://www.ebi.ac.uk/pdbsum/5i7m PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5i7m ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5i7m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5i7m OCA], [https://pdbe.org/5i7m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5i7m RCSB], [https://www.ebi.ac.uk/pdbsum/5i7m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5i7m ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/PRI2_HUMAN PRI2_HUMAN]] DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication.
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[https://www.uniprot.org/uniprot/PRI2_HUMAN PRI2_HUMAN] DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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==See Also==
==See Also==
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*[[RNA polymerase|RNA polymerase]]
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*[[RNA polymerase 3D structures|RNA polymerase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Chazin, W J]]
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[[Category: Chazin WJ]]
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[[Category: Salay, L E]]
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[[Category: Salay LE]]
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[[Category: Thompson, M K]]
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[[Category: Thompson MK]]
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[[Category: Dna replication]]
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[[Category: P58c]]
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[[Category: Primase]]
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[[Category: Replication]]
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Current revision

Crystal structure of Y345F mutant of human primase p58 iron-sulfur cluster domain

PDB ID 5i7m

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