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6cfi

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<StructureSection load='6cfi' size='340' side='right'caption='[[6cfi]], [[Resolution|resolution]] 3.36&Aring;' scene=''>
<StructureSection load='6cfi' size='340' side='right'caption='[[6cfi]], [[Resolution|resolution]] 3.36&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6cfi]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Baker's_yeast Baker's yeast]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6CFI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6CFI FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6cfi]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6CFI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6CFI FirstGlance]. <br>
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</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=T64:(6-4)PHOTOPRODUCT'>T64</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.3624191&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RAD4, YER162C ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=559292 Baker's yeast]), RAD23, YEL037C, SYGP-ORF29 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=559292 Baker's yeast])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=T64:(6-4)PHOTOPRODUCT'>T64</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6cfi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6cfi OCA], [http://pdbe.org/6cfi PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6cfi RCSB], [http://www.ebi.ac.uk/pdbsum/6cfi PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6cfi ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6cfi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6cfi OCA], [https://pdbe.org/6cfi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6cfi RCSB], [https://www.ebi.ac.uk/pdbsum/6cfi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6cfi ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/RAD4_YEAST RAD4_YEAST]] Involved in nucleotide excision repair of DNA damaged with UV light, bulky adducts, or cross-linking agents. [[http://www.uniprot.org/uniprot/RAD23_YEAST RAD23_YEAST]] Plays a central role both in proteasomal degradation of misfolded proteins and DNA repair. Central component of a complex required to couple deglycosylation and proteasome-mediated degradation of misfolded proteins in the endoplasmic reticulum that are retrotranslocated in the cytosol. Involved in DNA excision repair. May play a part in DNA damage recognition and/or in altering chromatin structure to allow access by damage-processing enzymes.
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[https://www.uniprot.org/uniprot/RAD4_YEAST RAD4_YEAST] Involved in nucleotide excision repair of DNA damaged with UV light, bulky adducts, or cross-linking agents.
==See Also==
==See Also==
*[[DNA repair protein Rad4|DNA repair protein Rad4]]
*[[DNA repair protein Rad4|DNA repair protein Rad4]]
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*[[UV excision repair protein|UV excision repair protein]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Baker's yeast]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Jeffrey, P D]]
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[[Category: Saccharomyces cerevisiae S288C]]
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[[Category: Min, J]]
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[[Category: Synthetic construct]]
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[[Category: Dna binding protein-dna complex]]
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[[Category: Jeffrey PD]]
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[[Category: Dna damage repair]]
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[[Category: Min J]]
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[[Category: Nucleotide excision repair]]
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[[Category: Ultraviolet]]
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[[Category: Xeroderma pigmentosum]]
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[[Category: Xpc]]
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Current revision

Crystal structure of Rad4-Rad23 bound to a 6-4 photoproduct UV lesion

PDB ID 6cfi

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