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6j3q

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==Capsid structure of a freshwater cyanophage Siphoviridae Mic1==
==Capsid structure of a freshwater cyanophage Siphoviridae Mic1==
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<StructureSection load='6j3q' size='340' side='right'caption='[[6j3q]], [[Resolution|resolution]] 3.53&Aring;' scene=''>
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<SX load='6j3q' size='340' side='right' viewer='molstar' caption='[[6j3q]], [[Resolution|resolution]] 3.53&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6j3q]] is a 26 chain structure with sequence from [http://en.wikipedia.org/wiki/Microcystis_phage_mic1 Microcystis phage mic1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6J3Q OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6J3Q FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6j3q]] is a 26 chain structure with sequence from [https://en.wikipedia.org/wiki/Microcystis_phage_Mic1 Microcystis phage Mic1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6J3Q OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6J3Q FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6j3q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6j3q OCA], [http://pdbe.org/6j3q PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6j3q RCSB], [http://www.ebi.ac.uk/pdbsum/6j3q PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6j3q ProSAT]</span></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.53&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6j3q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6j3q OCA], [https://pdbe.org/6j3q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6j3q RCSB], [https://www.ebi.ac.uk/pdbsum/6j3q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6j3q ProSAT]</span></td></tr>
</table>
</table>
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<div style="background-color:#fffaf0;">
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== Function ==
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== Publication Abstract from PubMed ==
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[https://www.uniprot.org/uniprot/A0A4Y5TR23_9CAUD A0A4Y5TR23_9CAUD]
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Cyanobacteria are the most abundant photosynthetic microorganisms, the global distribution of which is mainly regulated by the corresponding cyanophages. A systematic screening of water samples in the Lake Chaohu enabled us to isolate a freshwater siphocyanophage that infects Microcystis wesenbergii, thus termed Mic1. Using cryoelectron microscopy, we solved the 3.5-A structure of Mic1 capsid. The major capsid protein gp40 of an HK97-like fold forms two types of capsomers, hexons and pentons. The capsomers interact with each other via the interweaved N-terminal arms of gp40 in addition to a tail-in-mouth joint along the three-fold symmetric axis, resulting in the assembly of capsid in a mortise-and-tenon pattern. The novel-fold cement protein gp47 sticks at the two-fold symmetric axis and further fixes the capsid. These findings provide structural insights into the assembly of cyanophages, and set up a platform to explore the mechanism of specific interactions and co-evolution with cyanobacteria.
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Capsid Structure of a Freshwater Cyanophage Siphoviridae Mic1.,Jin H, Jiang YL, Yang F, Zhang JT, Li WF, Zhou K, Ju J, Chen Y, Zhou CZ Structure. 2019 Jul 30. pii: S0969-2126(19)30235-7. doi:, 10.1016/j.str.2019.07.003. PMID:31378451<ref>PMID:31378451</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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<div class="pdbe-citations 6j3q" style="background-color:#fffaf0;"></div>
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== References ==
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<references/>
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__TOC__
__TOC__
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</StructureSection>
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</SX>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Microcystis phage mic1]]
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[[Category: Microcystis phage Mic1]]
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[[Category: Chen, Y]]
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[[Category: Chen Y]]
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[[Category: Jiang, Y L]]
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[[Category: Jiang YL]]
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[[Category: Jin, H]]
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[[Category: Jin H]]
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[[Category: Ju, J]]
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[[Category: Ju J]]
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[[Category: Li, W F]]
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[[Category: Li WF]]
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[[Category: Yang, F]]
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[[Category: Yang F]]
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[[Category: Zhang, J T]]
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[[Category: Zhang JT]]
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[[Category: Zhou, C Z]]
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[[Category: Zhou CZ]]
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[[Category: Zhou, K]]
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[[Category: Zhou K]]
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[[Category: Capsid]]
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[[Category: Cyanophage]]
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[[Category: Siphoviridae]]
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[[Category: Virus]]
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Current revision

Capsid structure of a freshwater cyanophage Siphoviridae Mic1

6j3q, resolution 3.53Å

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