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6l4l
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of S. aureus CntK in inactive state== | |
| - | + | <StructureSection load='6l4l' size='340' side='right'caption='[[6l4l]], [[Resolution|resolution]] 2.00Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6l4l]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6L4L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6L4L FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr> |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6l4l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6l4l OCA], [https://pdbe.org/6l4l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6l4l RCSB], [https://www.ebi.ac.uk/pdbsum/6l4l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6l4l ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| - | [[Category: Luo | + | == Function == |
| + | [https://www.uniprot.org/uniprot/CNTK_STAAM CNTK_STAAM] Catalyzes the reversible interconversion of the L- and D-stereoisomers of histidine. Functions in the biosynthesis of the metallophore staphylopine, which is involved in the acquisition of nickel, cobalt, zinc, copper, and iron, and thus enables bacterial growth inside the host, where metal access is limited. Therefore, this enzyme probably contributes to staphylococcal virulence. Appears to be specific for histidine, as it cannot use L-alanine and L-methionine as substrate.<ref>PMID:27230378</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Staphylococcus aureus]] | ||
| + | [[Category: Ju Y]] | ||
| + | [[Category: Luo S]] | ||
| + | [[Category: Zhou H]] | ||
Current revision
Crystal structure of S. aureus CntK in inactive state
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