6le3
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of gluconate 5-dehydrogenase from Lentibacter algarum== | |
| + | <StructureSection load='6le3' size='340' side='right'caption='[[6le3]], [[Resolution|resolution]] 2.10Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[6le3]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Lentibacter_algarum Lentibacter algarum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6LE3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6LE3 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6le3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6le3 OCA], [https://pdbe.org/6le3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6le3 RCSB], [https://www.ebi.ac.uk/pdbsum/6le3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6le3 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/A0A1H3NGY9_9RHOB A0A1H3NGY9_9RHOB] | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | Gluconate 5-dehydrogenase (Ga5DH; EC 1.1.1.69) from Lentibacter algarum (LaGa5DH) was recombinantly expressed in Escherichia coli and purified to homogeneity. The protein was crystallized and the crystal structure was solved at 2.1 A resolution. The crystal belonged to the monoclinic system, with space group P1 and unit-cell parameters a = 55.42, b = 55.48, c = 79.16 A, alpha = 100.51, beta = 105.66, gamma = 97.99 degrees . The structure revealed LaGaDH to be a tetramer, with each subunit consisting of six alpha-helices and three antiparallel beta-hairpins. LaGa5DH has high structural similarity to other Ga5DH proteins, demonstrating that this enzyme is highly conserved. | ||
| - | + | Crystal structure of gluconate 5-dehydrogenase from Lentibacter algarum.,Tian D, Fu X, Cao W, Yuan H Acta Crystallogr F Struct Biol Commun. 2020 May 1;76(Pt 5):228-234. doi:, 10.1107/S2053230X20005336. Epub 2020 Apr 29. PMID:32356525<ref>PMID:32356525</ref> | |
| - | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |
| - | [[Category: | + | </div> |
| - | [[Category: Yuan | + | <div class="pdbe-citations 6le3" style="background-color:#fffaf0;"></div> |
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Lentibacter algarum]] | ||
| + | [[Category: Yuan H]] | ||
Current revision
Crystal structure of gluconate 5-dehydrogenase from Lentibacter algarum
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