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5kbd
From Proteopedia
(Difference between revisions)
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<StructureSection load='5kbd' size='340' side='right'caption='[[5kbd]], [[Resolution|resolution]] 2.80Å' scene=''> | <StructureSection load='5kbd' size='340' side='right'caption='[[5kbd]], [[Resolution|resolution]] 2.80Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5kbd]] is a 4 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[5kbd]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5KBD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5KBD FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5kbd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5kbd OCA], [https://pdbe.org/5kbd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5kbd RCSB], [https://www.ebi.ac.uk/pdbsum/5kbd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5kbd ProSAT]</span></td></tr> | |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/P73_HUMAN P73_HUMAN] Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein.<ref>PMID:11753569</ref> <ref>PMID:10203277</ref> <ref>PMID:18174154</ref> |
==See Also== | ==See Also== | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Huang | + | [[Category: Huang D]] |
| - | [[Category: Nguyen | + | [[Category: Nguyen HT]] |
| - | + | ||
| - | + | ||
Current revision
Structural Studies of Transcription Factor p73 DNA Binding Domain Bound to PA26 20-mer Response Element
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