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6e3a

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Current revision (06:17, 11 October 2023) (edit) (undo)
 
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<StructureSection load='6e3a' size='340' side='right'caption='[[6e3a]], [[Resolution|resolution]] 1.40&Aring;' scene=''>
<StructureSection load='6e3a' size='340' side='right'caption='[[6e3a]], [[Resolution|resolution]] 1.40&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6e3a]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Clostridium_thermocellum Clostridium thermocellum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6E3A OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6E3A FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6e3a]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Acetivibrio_thermocellus_ATCC_27405 Acetivibrio thermocellus ATCC 27405]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6E3A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6E3A FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=COA:COENZYME+A'>COA</scene>, <scene name='pdbligand=HQG:[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]+[(2~{R},3~{S},4~{R},5~{R})-3,4-bis(oxidanyl)-5-phosphonooxy-oxolan-2-yl]methyl+hydrogen+phosphate'>HQG</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.4&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">kptA, Cthe_3059 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=203119 Clostridium thermocellum])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=COA:COENZYME+A'>COA</scene>, <scene name='pdbligand=HQG:[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]+[(2~{R},3~{S},4~{R},5~{R})-3,4-bis(oxidanyl)-5-phosphonooxy-oxolan-2-yl]methyl+hydrogen+phosphate'>HQG</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6e3a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6e3a OCA], [http://pdbe.org/6e3a PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6e3a RCSB], [http://www.ebi.ac.uk/pdbsum/6e3a PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6e3a ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6e3a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6e3a OCA], [https://pdbe.org/6e3a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6e3a RCSB], [https://www.ebi.ac.uk/pdbsum/6e3a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6e3a ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/KPTA_CLOTH KPTA_CLOTH]] Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''-cyclic phosphate (APPR>P). May function as an ADP-ribosylase.
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[https://www.uniprot.org/uniprot/KPTA_ACET2 KPTA_ACET2] Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''-cyclic phosphate (APPR>P). May function as an ADP-ribosylase.[HAMAP-Rule:MF_00299]
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<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Clostridium thermocellum]]
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[[Category: Acetivibrio thermocellus ATCC 27405]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Banerjee, A]]
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[[Category: Banerjee A]]
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[[Category: Goldgur, Y]]
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[[Category: Goldgur Y]]
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[[Category: Shuman, S]]
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[[Category: Shuman S]]
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[[Category: Kpta]]
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[[Category: Tpt1]]
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[[Category: Transferase]]
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[[Category: Trpt1]]
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Current revision

tRNA 2'-phosphotransferase

PDB ID 6e3a

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