This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
6lfg
From Proteopedia
(Difference between revisions)
m (Protected "6lfg" [edit=sysop:move=sysop]) |
|||
| (One intermediate revision not shown.) | |||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Cryo-EM structure of the Drosophila CTP synthase product-bound filament== | |
| - | + | <StructureSection load='6lfg' size='340' side='right'caption='[[6lfg]], [[Resolution|resolution]] 9.58Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6lfg]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6LFG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6LFG FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 9.58Å</td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6lfg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6lfg OCA], [https://pdbe.org/6lfg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6lfg RCSB], [https://www.ebi.ac.uk/pdbsum/6lfg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6lfg ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/PYRG_DROME PYRG_DROME] Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Constitutes the rate-limiting enzyme in the synthesis of cytosine nucleotides (By similarity). Isoform 1 is required for cytoophidium assembly in female germline cells.<ref>PMID:23459760</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Drosophila melanogaster]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Chen-Jun G]] | ||
| + | [[Category: Ji-long L]] | ||
| + | [[Category: Xian Z]] | ||
Current revision
Cryo-EM structure of the Drosophila CTP synthase product-bound filament
| |||||||||||
