5u4w

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==Cryo-EM Structure of Immature Zika Virus==
==Cryo-EM Structure of Immature Zika Virus==
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<StructureSection load='5u4w' size='340' side='right'caption='[[5u4w]], [[Resolution|resolution]] 9.10&Aring;' scene=''>
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<SX load='5u4w' size='340' side='right' viewer='molstar' caption='[[5u4w]], [[Resolution|resolution]] 9.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5u4w]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Zikv Zikv] and [http://en.wikipedia.org/wiki/Zika_virus Zika virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5U4W OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5U4W FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5u4w]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Zika_virus Zika virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5U4W OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5U4W FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 9.1&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5u4w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5u4w OCA], [http://pdbe.org/5u4w PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5u4w RCSB], [http://www.ebi.ac.uk/pdbsum/5u4w PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5u4w ProSAT]</span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5u4w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5u4w OCA], [https://pdbe.org/5u4w PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5u4w RCSB], [https://www.ebi.ac.uk/pdbsum/5u4w PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5u4w ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/O11875_9FLAV O11875_9FLAV] Envelope protein E binding to host cell surface receptor is followed by virus internalization through clathrin-mediated endocytosis. Envelope protein E is subsequently involved in membrane fusion between virion and host late endosomes. Synthesized as a homodimer with prM which acts as a chaperone for envelope protein E. After cleavage of prM, envelope protein E dissociate from small envelope protein M and homodimerizes (By similarity).[SAAS:SAAS026470_004_099774]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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<references/>
<references/>
__TOC__
__TOC__
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</StructureSection>
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</SX>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Zika virus]]
[[Category: Zika virus]]
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[[Category: Zikv]]
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[[Category: Buda G]]
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[[Category: Buda, G]]
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[[Category: Jiang W]]
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[[Category: Jiang, W]]
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[[Category: Klose T]]
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[[Category: Klose, T]]
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[[Category: Kuhn RJ]]
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[[Category: Kuhn, R J]]
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[[Category: Mangala Prasad V]]
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[[Category: Miller, A S]]
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[[Category: Miller AS]]
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[[Category: Prasad, V Mangala]]
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[[Category: Rossmann MG]]
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[[Category: Rossmann, M G]]
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[[Category: Sirohi D]]
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[[Category: Sirohi, D]]
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[[Category: Immature zika virus]]
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[[Category: Viral protein]]
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[[Category: Virus]]
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Current revision

Cryo-EM Structure of Immature Zika Virus

5u4w, resolution 9.10Å

Proteopedia Page Contributors and Editors (what is this?)

OCA

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