Rho guanine nucleotide exchange factor 3D structures

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(New page: == 3D Structures of Rho guanine nucleotide exchange factor == Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} {{#tree:id=OrganizedByTopic|openlevels=0| *Rho ...)
Current revision (10:08, 16 October 2023) (edit) (undo)
 
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*Rho guanine nucleotide exchange factor 1 (P115-RhoGEF)
+
*GEF guanine nucleotide exchange factor 1 (P115-GEFGEF)
-
**[[1iap]] – hGEF N terminal - human<br />
+
**[[1iap]] – hGEF N terminal RGS domain 42-252 - human<br />
-
**[[3odo]], [[3odw]], [[3odx]] – hGEF DH/PH domain <br />
+
**[[3odo]], [[3odw]], [[3odx]] – hGEF DH/PH domain 353-766<br />
**[[3p6a]] – hGEF DH/PH domain (mutant)<br />
**[[3p6a]] – hGEF DH/PH domain (mutant)<br />
-
**[[1shz]], [[3ab3]] – hGEF N terminal + guanine nucleotide-binding protein<br />
+
**[[1shz]], [[3ab3]] – hGEF N terminal RGS domain + guanine nucleotide-binding protein<br />
-
*Rho guanine nucleotide exchange factor 2
+
*GEF guanine nucleotide exchange factor 2
-
**[[5efx]] - hGEF residues 439-582<br />
+
**[[8bnt]] – hGEF-H1 DH domain 206-448 + RhoA <br />
 +
**[[7g80]], [[7g81]], [[7g82]], [[7g83]], [[7g84]], [[7g85]], [[7g86]], [[7g88]], [[7g89]], [[7g8a]], [[7g8b]], [[7g8c]], [[7g8d]], [[7g8e]], [[7g8f]], [[7g8g]], [[7g8h]], [[7g8i]], [[7g8j]], [[7g8k]], [[7g8l]], [[7g8m]], [[7g8n]], [[7g8o]], [[7g8p]], [[7g8q]], [[7g8r]], [[7g87]], [[7g8s]], [[7g8t]], [[7g8u]], [[7g8v]], [[7g8w]], [[7g8x]], [[7g8y]], [[7g8z]], [[7g90]], [[7g91]], [[7g92]], [[7g93]], [[7g94]], [[7g95]], [[7g96]], [[7g97]], [[7g98]], [[7g99]], [[7g9a]], [[7g9b]], [[7g9c]], [[7g9d]], [[7g9e]], [[7g9f]], [[7g9g]], [[7g9h]], [[7g9i]], [[7g9j]] – hGEF-H1 DH domain + RhoA + inhibitor<br />
 +
**[[5efx]] – hGEF-H1 439-582 <br />
-
*Rho guanine nucleotide exchange factor 4 (Asef)
+
*GEF guanine nucleotide exchange factor 3
-
**[[2dx1]], [[2pz1]] – hGEF <br />
+
**[[2z0q]] – mGEF DH/PH domain - mouse<br />
-
**[[3nmx]], [[3nmz]] – hGEF + APC variant protein<br />
+
-
*Rho guanine nucleotide exchange factor 6
+
*GEF guanine nucleotide exchange factor 4 (Asef)
-
**[[1ujy]] – hGEF SH3 domain - NMR<br />
+
**[[2dx1]] – hGEF 59-540<br />
-
**[[1wyr]] – hGEF CH domain - NMR<br />
+
**[[2pz1]] – hGEF 137-599<br />
 +
**[[3nmx]], [[3nmz]] – hGEF 170-276 + APC<br />
-
*Rho guanine nucleotide exchange factor 7 (β-PIX)
+
*GEF guanine nucleotide exchange factor 6
-
**[[1by1]] – hGEF DH domain - NMR<br />
+
**[[1ujy]] – hGEF SH3 domain 160-222 - NMR<br />
-
**[[2l3g]] – hGEF CH domain - NMR<br />
+
**[[1wyr]] – hGEF CH domain 4-111 - NMR<br />
-
**[[2esw]] – GEF SH3 domain – mouse<br />
+
 
 +
*GEF guanine nucleotide exchange factor 7 (b-PIX)
 +
 
 +
**[[1by1]] – hGEF DH domain 81-289 - NMR<br />
 +
**[[2l3g]] – hGEF CH domain 1-137 - NMR<br />
 +
**[[2esw]] – mGEF SH3 domain 7-63 <br />
**[[2g6f]] – rGEF SH3 domain – rat<br />
**[[2g6f]] – rGEF SH3 domain – rat<br />
-
**[[2w6b]] – rGEF coiled-coil domain <br />
+
**[[2w6b]] – rGEF coiled-coil domain 588-638 <br />
-
*Rho guanine nucleotide exchange factor 7 complex with peptide
+
*GEF guanine nucleotide exchange factor 7 complex with peptide
**[[2ak5]] – hGEF SH3 domain + CBL-b peptide <br />
**[[2ak5]] – hGEF SH3 domain + CBL-b peptide <br />
**[[2df6]] – hGEF SH3 domain + PAK-1 peptide <br />
**[[2df6]] – hGEF SH3 domain + PAK-1 peptide <br />
**[[1zsg]] – hGEF residues 179-243 + PAK-1 peptide – NMR<br />
**[[1zsg]] – hGEF residues 179-243 + PAK-1 peptide – NMR<br />
-
**[[5sxp]] - hGEF residues 183-243 + E3 ubiquitin-protein ligase itchy<br />
 
**[[2p4r]] – rGEF SH3 domain + E3 ubiquitin protein ligase peptide <br />
**[[2p4r]] – rGEF SH3 domain + E3 ubiquitin protein ligase peptide <br />
**[[3l4f]] – rGEF coiled-coil domain + SHANK1 PDZ domain <br />
**[[3l4f]] – rGEF coiled-coil domain + SHANK1 PDZ domain <br />
-
*Rho guanine nucleotide exchange factor 8 (PRONE8)
+
*GEF guanine nucleotide exchange factor 8 (PRONE8)
**[[3eo2]] – hGEF residues 161-373 <br />
**[[3eo2]] – hGEF residues 161-373 <br />
-
**[[4xh9]] – hGEF DH/PH domain + transforming protein RhoA <br />
+
**[[4xh9]] – hGEF DH/PH domain + transforming protein GEFA <br />
-
**[[2ntx]] – AtGEF PRONE domain – ''Arabidopasis thaliana''<br />
+
**[[2ntx]] – AtGEF PRONE domain 76-440 – Arabidopasis thaliana<br />
**[[2wbl]] – AtGEF PRONE domain + GTPase ROP7 <br />
**[[2wbl]] – AtGEF PRONE domain + GTPase ROP7 <br />
**[[2nty]] – AtGEF PRONE domain + GTPase ROP4 + GDP <br />
**[[2nty]] – AtGEF PRONE domain + GTPase ROP4 + GDP <br />
-
*Rho guanine nucleotide exchange factor 9 (collybistin)
+
*GEF guanine nucleotide exchange factor 9 (collybistin)
**[[2ysq]] – hGEF SH3 domain - NMR<br />
**[[2ysq]] – hGEF SH3 domain - NMR<br />
**[[4mt6]], [[4mt7]] – rGEF (mutant)<br />
**[[4mt6]], [[4mt7]] – rGEF (mutant)<br />
-
**[[2dfk]] – rGEF + CDC42 <br />
+
**[[2dfk]] – rGEF II + CDC42 <br />
-
*Rho guanine nucleotide exchange factor 11
+
*GEF guanine nucleotide exchange factor 11
-
**[[2dls]] – hGEF PDZ domain - NMR<br />
+
**[[2dls]] – hGEF PDZ domain 44-123 - NMR<br />
-
**[[5tyt]] - hGEF PDZ domain/CXCR2 peptide<br />
+
**[[5e6p]] – hGEF PDZ domain + plexin-B2 <br />
-
**[[3kz1]], [[3t06]], [[5jhg]], [[5jhh]] – hGEF DH/PH domain + transforming protein RhoA <br />
+
**[[3kz1]], [[3t06]] – hGEF DH/PH domain 710-1085 + transforming protein GEFA <br />
-
**[[1xcg]] – hGEF DH/PH domain + transforming protein RhoA - NMR<br />
+
**[[5jhg]] – hGEF DH/PH domain + transforming protein RhoA <br />
-
**[[3cx6]] – rGEF RGS domain + guanine nucleotide-binding protein <br />
+
**[[5jhh]] – hGEF DH/PH domain + transforming protein RhoA + inhibitor<br />
-
**[[5e6p]] - mGEF PDZ domain + plexin-B2<br />
+
**[[1xcg]] – hGEF DH/PH domain + transforming protein GEFA - NMR<br />
 +
**[[3cx6]], [[3cx8]] – rGEF RGS domain 307-508 + guanine nucleotide-binding protein <br />
-
*Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF)
+
*GEF guanine nucleotide exchange factor 12 (Leukemia-associated GEFGEF)
-
**[[1txd]] – hGEF DH/PH domain <br />
+
**[[1txd]] – hGEF DH/PH domain 764-1138<br />
-
**[[2omj]] – hGEF PDZ domain <br />
+
**[[2omj]] – hGEF PDZ domain 67-151<br />
-
**[[1x86]] – hGEF DH/PH domain (mutant) + transforming protein RhoA <br />
+
**[[1x86]] – hGEF DH/PH domain (mutant) + transforming protein GEFA <br />
**[[2os6]] – hGEF PDZ domain + plexin peptide – NMR<br />
**[[2os6]] – hGEF PDZ domain + plexin peptide – NMR<br />
-
*Rho guanine nucleotide exchange factor 16
+
*GEF guanine nucleotide exchange factor 16 (Ephexin-4)
-
**[[1x6b]] – hGEF SH3 domain - NMR<br />
+
**[[1x6b]] – hGEF SH3 domain 334-399 - NMR<br />
 +
**[[7cso]], [[7csp]], [[7csr]] – mGEF 261-713 (mutant)<br />
*GEF guanine nucleotide exchange factor 18
*GEF guanine nucleotide exchange factor 18
-
**[[6bcb]] – mGEF + transforming protein RhoA<br />
+
**[[6bcb]] – mGEF 302-444 + transforming protein RhoA<br />
 +
 
 +
*GEF guanine nucleotide exchange factor 25
 +
 
 +
**[[2rgn]] – hGEF 149-502 + transforming protein RhoA + guanine nucleotide-binding protein G(I)<br />
*GEF guanine nucleotide exchange factor 28
*GEF guanine nucleotide exchange factor 28
-
**[[6bc1]] – hGEF + Ras-related C3 botulinum toxin substrate 1<br />
+
**[[6bc1]] – hGEF PH domain 1049-1194 + Ras-related C3 botulinum toxin substrate 1<br />
-
**[[6bc0]] – hGEF + transforming protein RhoA<br />
+
**[[6bc0]] – hGEF PH domain + transforming protein RhoA<br />
 +
 
}}
}}
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[[Category:Topic Page]]

Current revision

3D Structures of Rho guanine nucleotide exchange factor

Updated on 16-October-2023

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel

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