6jpu
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==CryoEM structure of Abo1 hexamer - apo complex== | |
| - | + | <SX load='6jpu' size='340' side='right' viewer='molstar' caption='[[6jpu]], [[Resolution|resolution]] 4.27Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6jpu]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Schizosaccharomyces_pombe_972h- Schizosaccharomyces pombe 972h-]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6JPU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6JPU FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 4.27Å</td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6jpu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6jpu OCA], [https://pdbe.org/6jpu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6jpu RCSB], [https://www.ebi.ac.uk/pdbsum/6jpu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6jpu ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/ATD2_SCHPO ATD2_SCHPO] ATPase histone chaperone which facilitates loading of histone H3-H4 onto DNA in an ATP-dependent manner (PubMed:31848341, PubMed:33658433). Plays a genome-wide role in nucleosome organization and establishment of chromatin (PubMed:26582768, PubMed:31848341). Also plays a role in heterochromatin assembly by stabilizing recruitment of the histone methyltransferase clr4 to methylated histone H3, to promote the transition from H3K9me2 to H3K9me3 (PubMed:32269268).<ref>PMID:26582768</ref> <ref>PMID:31848341</ref> <ref>PMID:32269268</ref> <ref>PMID:33658433</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </SX> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Schizosaccharomyces pombe 972h-]] | ||
| + | [[Category: Cho C]] | ||
| + | [[Category: Jang J]] | ||
| + | [[Category: Song JJ]] | ||
Current revision
CryoEM structure of Abo1 hexamer - apo complex
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